Transcription Factor

Accessions: 3il2_B (3D-footprint 20231221)
Names: Redox-sensing transcriptional repressor rex, REX_THET2
Organisms: strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q72I39
Length: 206
Pfam Domains: 2-50 Putative DNA-binding protein N-terminus
79-174 CoA binding domain
Sequence:
(in bold interface residues)
1 MKVPEAAISRLITYLRILEELEAQGVHRTSSEQLGELAQVTAFQVRKDLSYFGSYGTRGV 60
61 GYTVPVLKRELRHILGLNRKWGLCIVGMGDLGSALADYPGFGESFELRGFFDVDPEKVGR 120
121 PVRGGVIEHVDLLPQRVPGRIEIALLTVPREAAQKAADLLVAAGIKGILNFAPVVLEVPK 180
181 EVAVENVDFLAGLTRLSFAILNPKWR
Interface Residues: 43, 44, 46, 47, 50, 51, 58, 60
3D-footprint Homologues: 3ikt_B, 3ket_A, 3wgi_D, 7wb3_B
Binding Motifs: 3il2_AB GAGnnnnnnnnCnCngc
3il2_B CnCngc
Binding Sites: 3il2_D
3il2_C
Publications: McLaughlin K.J, Strain-Damerell C.M, Xie K, Brekasis D, Soares A.S, Paget M.S, Kielkopf C.L. Structural basis for NADH/NAD+ redox sensing by a Rex family repressor. Molecular cell 38:563-75 (2010). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.