Transcription Factor
| Accessions: | 6g1l_A (3D-footprint 20231221) |
| Names: | Microphthalmia-associated transcription factor, MITF_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q08874 |
| Length: | 79 |
| Pfam Domains: | 6-59 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 AKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQR 60 61 EQQRAKDLENRQKKLEHAN |
| Interface Residues: | 7, 10, 11, 13, 14, 15, 17, 18, 42, 44 |
| 3D-footprint Homologues: | 1a0a_B, 7ssa_L, 5v0l_A, 4zpk_A, 7d8t_A, 7xi3_A, 5eyo_A, 1am9_A, 7f2f_B, 5nj8_D, 4h10_A, 6g1l_A, 5gnj_I, 7rcu_E, 5sy7_B, 4h10_B, 8osl_O, 5i50_B, 8osl_P, 2ypa_B, 1an4_A, 5nj8_C, 6od3_F, 2ypa_A, 5v0l_B, 7xi3_B |
| Binding Motifs: | 6g1l_A CgTGa |
| Binding Sites: | 6g1l_B |
| Publications: | Möller K, Sigurbjornsdottir S, Arnthorsson AO, Pogenberg V, Dilshat R, Fock V, Brynjolfsdottir SH, Bindesboll C, Bessadottir M, Ogmundsdottir HM, Simonsen A, Larue L, Wilmanns M, Thorsson V, Steingrimsson E, Ogmundsdottir MH. MITF has a central role in regulating starvation-induced autophagy in melanoma. Sci Rep 9:1055 (2019). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.