Transcription Factor
| Accessions: | UP00297A (UniPROBE 20160601) |
| Names: | "LPZ9w, Sterol uptake protein 2, Sut2, YPR009W" |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q12286 |
| Description: | Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p |
| Length: | 183 |
| Sequence: (in bold interface residues) | 1 MQKESEKTKLPKLGCPTEYTEYYKTVSSGETTDSAVVSSIATNRLKRKRQRDGPSCDSCR 60 61 IKKIKCNATIIIFLQDRNLISSISSNLHYTLSQDDINQFRMKFFRKLPDVMGTYEVIKHL 120 121 DKIVLFKACTSCSRRNQKNGKCLFSRGFTKSDMNVFPKINSKLKDKSIFEMTVDDYVAAG 180 181 FQT |
| Interface Residues: | 45, 49, 50, 54, 60, 62, 63, 64, 65, 84, 85, 86, 87, 88, 89, 125, 143, 145, 147, 149, 150, 152, 154, 156, 158, 160 |
| 3D-footprint Homologues: | 1i3j_A, 1f5e_P, 1pyi_A, 7uik_T, 1d66_B, 3coq_A, 8dc2_A, 6jhe_A, 4yit_A |
| Binding Motifs: | UP00297A_1 wkrwwrAASTCCGArmwwbw |
| Binding Sites: | AAACTCCG AAAGTCCG AACTCCGA AACTCCGC AACTCCGG AACTCCGT AAGTCCGA AAGTCCGG ACTCCGAA ACTCCGAG ACTCCGAT ACTCCGGA ATACTCCG CAACTCCG CGGACTTC CGGAGTTA CGGAGTTC TACTCCGA ACTCCGAC CCGGAGTA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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