Transcription Factor
| Accessions: | 2ql2_D (3D-footprint 20231221) |
| Names: | Beta-cell E-box transcriptional activator 2, Beta2, NDF1_MOUSE, NeuroD1, Neurogenic differentiation factor 1 |
| Organisms: | Mus musculus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q60867 |
| Length: | 57 |
| Pfam Domains: | 1-52 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 RRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILR |
| Interface Residues: | 2, 5, 6, 8, 9, 10, 12, 13 |
| 3D-footprint Homologues: | 7z5k_B, 2ypa_A, 6od3_F, 2ql2_D, 2ypa_B, 2ql2_A |
| Binding Motifs: | 2ql2_CD CCAGntGG |
| Binding Sites: | 2ql2_G 2ql2_H |
| Publications: | Longo A, Guanga G.P, Rose R.B. Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition. Biochemistry 47:218-29 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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