Transcription Factor
| Accessions: | ZNF45 (humanC2H2ZF-ChIP Feb2015), Q02386 (JASPAR 2024) |
| Names: | ENSG00000124459, Q02386, ZNF45, BRC1744, Zinc finger protein 13, Zinc finger protein 45, Zinc finger protein KOX5, ZNF45_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | humanC2H2ZF-ChIP Feb2015 1, JASPAR 2024 2 1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | TF family: C2H2;KRAB experiment: ChIP-seq/MEME/B1H-RC |
| Length: | 682 |
| Pfam Domains: | 8-48 KRAB box 184-202 Zinc-finger double domain 191-215 C2H2-type zinc finger 192-214 C2H2-type zinc finger 192-214 Zinc finger, C2H2 type 268-286 Zinc-finger double domain 276-298 C2H2-type zinc finger 276-298 Zinc finger, C2H2 type 291-314 Zinc-finger double domain 303-317 C2H2-type zinc finger 304-326 C2H2-type zinc finger 304-326 Zinc finger, C2H2 type 319-343 Zinc-finger double domain 331-343 C2H2-type zinc finger 332-354 Zinc finger, C2H2 type 332-354 C2H2-type zinc finger 346-370 Zinc-finger double domain 359-382 C2H2-type zinc finger 360-382 C2H2-type zinc finger 360-382 Zinc finger, C2H2 type 374-397 Zinc-finger double domain 387-410 C2H2-type zinc finger 388-410 C2H2-type zinc finger 388-410 Zinc finger, C2H2 type 402-426 Zinc-finger double domain 416-438 C2H2-type zinc finger 416-438 Zinc finger, C2H2 type 416-431 C2H2-type zinc finger 431-454 Zinc-finger double domain 443-466 C2H2-type zinc finger 444-466 C2H2-type zinc finger 444-466 Zinc finger, C2H2 type 458-482 Zinc-finger double domain 471-490 C2H2-type zinc finger 472-494 C2H2-type zinc finger 472-494 Zinc finger, C2H2 type 486-510 Zinc-finger double domain 499-522 C2H2-type zinc finger 500-522 C2H2-type zinc finger 500-522 Zinc finger, C2H2 type 514-538 Zinc-finger double domain 528-550 C2H2-type zinc finger 528-548 Zinc finger, C2H2 type 543-565 Zinc-finger double domain 556-578 Zinc finger, C2H2 type 556-575 C2H2-type zinc finger 570-594 Zinc-finger double domain 584-606 Zinc finger, C2H2 type 584-606 C2H2-type zinc finger 584-606 C2H2-type zinc finger 599-622 Zinc-finger double domain 611-629 C2H2-type zinc finger 612-634 Zinc finger, C2H2 type 612-634 C2H2-type zinc finger 627-650 Zinc-finger double domain 639-662 C2H2-type zinc finger 640-662 C2H2-type zinc finger 640-662 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MTKSKEAVTFKDVAVVFSEEELQLLDLAQRKLYRDVMLENFRNVVSVGHQSTPDGLPQLE 60 61 REEKLWMMKMATQRDNSSGAKNLKEMETLQEVGLRYLPHEELFCSQIWQQITRELIKYQD 120 121 SVVNIQRTGCQLEKRDDLHYKDEGFSNQSSHLQVHRVHTGEKPYKGEHCVKSFSWSSHLQ 180 181 INQRAHAGEKPYKCEKCDNAFRRFSSLQAHQRVHSRAKSYTNDASYRSFSQRSHLPHHQR 240 241 VPTGENPYKYEECGRNVGKSSHCQAPLIVHTGEKPYKCEECGVGFSQRSYLQVHLKVHTG 300 301 KKPYKCEECGKSFSWRSRLQAHERIHTGEKPYKCNACGKSFSYSSHLNIHCRIHTGEKPY 360 361 KCEECGKGFSVGSHLQAHQISHTGEKPYKCEECGKGFCRASNLLDHQRGHTGEKPYQCDA 420 421 CGKGFSRSSDFNIHFRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCGTCGKG 480 481 FSRSSDLNVHCRIHTGEKPYKCERCGKAFSQFSSLQVHQRVHTGEKPYQCAECGKGFSVG 540 541 SQLQAHQRCHTGEKPYQCEECGKGFCRASNFLAHRGVHTGEKPYRCDVCGKRFRQRSYLQ 600 601 AHQRVHTGERPYKCEECGKVFSWSSYLQAHQRVHTGEKPYKCEECGKGFSWSSSLIIHQR 660 661 VHADDEGDKDFPSSEDSHRKTR |
| Interface Residues: | 214, 215, 262, 287, 288, 289, 290, 291, 292, 293, 295, 297, 301, 314, 315, 317, 318, 321, 343, 345, 346, 348, 349, 371, 372, 373, 374, 376, 377, 379, 380, 383, 388, 399, 400, 401, 402, 405, 426, 427, 428, 429, 430, 433, 454, 455, 456, 457, 458, 461, 482, 483, 484, 485, 486, 488, 489, 510, 511, 512, 513, 514, 515, 516, 517, 538, 539, 540, 541, 542, 544, 545, 566, 567, 568, 569, 570, 573, 575, 594, 595, 596, 597, 598, 601, 602, 604, 607, 621, 623, 624, 625, 626, 627, 629, 630, 633, 650, 651, 652, 653, 654, 656, 657 |
| 3D-footprint Homologues: | 6dnw_A, 8gn3_A, 1ubd_C, 8cuc_F, 6wmi_A, 5v3j_F, 2lt7_A, 8ssq_A, 2i13_A, 6blw_A, 5kkq_D, 5ei9_F, 5yj3_D, 2jpa_A, 2kmk_A, 7w1m_H, 1llm_D, 5und_A, 5yel_A, 5k5l_F, 4x9j_A, 2wbs_A, 1f2i_J, 5k5i_A, 7n5w_A, 8ssu_A, 1mey_C, 2drp_D, 6u9q_A, 2gli_A, 1g2f_F, 7eyi_G, 8h9h_G, 6e94_A, 7ysf_A, 3uk3_C, 6ml4_A, 7y3l_A, 7y3m_I, 1tf3_A, 1tf6_A, 6jnm_A, 5kl3_A, 4m9v_C, 6a57_A, 7txc_E |
| Binding Motifs: | ZNF45_ChIP ATAACArAATCCAGa UN0325.1 svrCCGGAAGTGrcgbss UN0325.2 CCGGAAGTG |
| Binding Sites: | UN0325.1.1 UN0325.1.10 UN0325.1.11 UN0325.1.12 UN0325.1.13 UN0325.1.14 UN0325.1.15 UN0325.1.16 UN0325.1.17 UN0325.1.18 UN0325.1.19 UN0325.1.2 UN0325.1.20 UN0325.1.3 UN0325.1.4 UN0325.1.5 UN0325.1.6 UN0325.1.7 UN0325.1.8 UN0325.1.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.