Transcription Factor
Accessions: | 5x07_F (3D-footprint 20231221) |
Names: | Forkhead box protein A2, FOXA2_HUMAN, Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B, TCF-3B, Transcription factor 3B |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q9Y261 |
Length: | 85 |
Pfam Domains: | 5-84 Fork head domain |
Sequence: (in bold interface residues) | 1 GPHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFN 60 61 DCFLKVPRSPDKPGKGSFWTLHPDS |
Interface Residues: | 45, 48, 50, 51, 52, 54, 55, 56, 58, 59, 68, 75 |
3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3qrf_G |
Binding Motifs: | 5x07_F TAAACA |
Binding Sites: | 5x07_D 5x07_E |
Publications: | Li J, Dantas Machado AC, Guo M, Sagendorf JM, Zhou Z, Jiang L, Chen X, Wu D, Qu L, Chen Z, Chen L, Rohs R, Chen Y. Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site. Biochemistry 56:3745-3753 (2017). [Pubmed] |
Related annotations: | PaperBLAST |
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