Transcription Factor

Accessions: 5x07_F (3D-footprint 20231221)
Names: Forkhead box protein A2, FOXA2_HUMAN, Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B, TCF-3B, Transcription factor 3B
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q9Y261
Length: 85
Pfam Domains: 5-84 Fork head domain
Sequence:
(in bold interface residues)
1 GPHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFN 60
61 DCFLKVPRSPDKPGKGSFWTLHPDS
Interface Residues: 45, 48, 50, 51, 52, 54, 55, 56, 58, 59, 68, 75
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3qrf_G
Binding Motifs: 5x07_F TAAACA
Binding Sites: 5x07_D
5x07_E
Publications: Li J, Dantas Machado AC, Guo M, Sagendorf JM, Zhou Z, Jiang L, Chen X, Wu D, Qu L, Chen Z, Chen L, Rohs R, Chen Y. Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site. Biochemistry 56:3745-3753 (2017). [Pubmed]
Related annotations: PaperBLAST

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