Transcription Factor
| Accessions: | UP00051A (UniPROBE 20160601) |
| Names: | Sox-8, Sox8, SRY-box containing gene 8, Transcription factor SOX-8 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q04886 |
| Description: | SRY-box containing gene 8: SRY-box containing gene 8, mRNA (cDNA clone MGC:78314 IMAGE:6306276), complete cds |
| Length: | 101 |
| Pfam Domains: | 17-85 HMG (high mobility group) box 18-80 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 MPVRGGGGGTLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSE 60 61 SEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKTGRSDS |
| Interface Residues: | 19, 22, 24, 25, 28, 32, 40, 41, 43, 44, 45, 48, 86, 90 |
| 3D-footprint Homologues: | 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 3tq6_B, 1j5n_A, 6jrp_D, 2lef_A, 1hry_A |
| Binding Motifs: | UP00051A_1 kkatywATTGTTmwkwa UP00051A_2 acATTCAtgamass |
| Binding Sites: | ATTATAAT AAAACAAT AAACAATT AACAATAG AACAATTG AAGACAAT AATGAATT AATTGTTA AATTGTTC ACAACAAT ACAATTGA ACAATTGT AGAACAAT ATGAATTA ATGAATTG ATTCATTC ATTGTTAA ATTGTTCG ATTGTTTC GAACAATA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.