Transcription Factor

Accessions: 6gys_C (3D-footprint 20231221)
Names: CBF3B_YEAST, Centromere DNA-binding protein complex CBF3 subunit B, Centromere protein 3
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P40969
Length: 573
Pfam Domains: 7-40 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 TQLKSKHPCSVCTRRKVKCDRMIPCGNCRKRGQDSECMKSTITASSSKEYLPDLLLFWQN 60
61 YEYWITNIGLYKTKQRDLTRTPANLDTDTEECMFWMNYLQKDQSFQLMNFAMENLGALYF 120
121 GSIGDISELYLRVEQYWDRRADKNHSVDGKYWDALIWSVFTMCIYYMPVEKLAEIFSVYP 180
181 LHEYLGSNKRLNWEDGMQLVMCQNFARCSLFQLKQCDFMAHPDIRLVQAYLILATTTFPY 240
241 DEPLLANSLLTQCIHTFKNFHVDDFRPLLNDDPVESIAKVTLGRIFYRLCGCDYLQSGPR 300
301 KPIALHTEVSSLLQHAAYLQDNSTEVLYWKIISLDRDLDQYLNKSSKPPLKTLDAIRREL 360
361 DIFQYKVDSLEEDFRSNNSRFQKFIALFQISTVSWKLFKMYLIYYDTADSLLKVIHYSKV 420
421 IISLIVNNFHAKSEFFNRHPMVMQTITRVVSFISFYQIFVESAAVKQLLVDLTELTANLP 480
481 TIFGSKLDKLVYLTERLSKLKLLWDKVQLLDSGDSFYHPVFKILQNDIKIIELKNDEMFS 540
541 LIKGLGSLVPLNSDFRTIVEEFQSEYNISDILS
Interface Residues: 2, 3, 4, 13, 15, 16, 17, 18, 30, 31, 42, 44, 45, 314, 315, 318, 351
3D-footprint Homologues: 1f5e_P, 6o19_A, 1hwt_C, 1pyi_A, 1zme_D, 6gys_C, 1d66_B
Binding Motifs: 6gys_ACEHJL CnnnnannnnnnnnngAnnT
Publications: Yan K, Zhang Z, Yang J, McLaughlin SH, Barford D. Architecture of the CBF3-centromere complex of the budding yeast kinetochore. Nat Struct Mol Biol 25:1103-1110 (2018). [Pubmed]
Related annotations: PaperBLAST

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