Transcription Factor
| Accessions: | 1k78_A (3D-footprint 20231221), 1k78_E (3D-footprint 20231221), 1mdm_A (3D-footprint 20231221) |
| Names: | B-cell-specific transcription factor, BSAP, Paired box protein Pax-5, Paired Box Protein Pax5, PAX5_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q02548 |
| Length: | 124 |
| Pfam Domains: | 2-122 'Paired box' domain |
| Sequence: (in bold interface residues) | 1 GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSI 60 61 KPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRI 120 121 IRTK |
| Interface Residues: | 11, 43, 44, 46, 48, 49, 65, 68, 71, 113, 114, 115, 116, 118, 119, 122 |
| 3D-footprint Homologues: | 1pdn_C, 6pax_A, 1k78_A |
| Binding Motifs: | 1k78_A CCAnTnnanCnTnTCT 1k78_EF CGGAGAnnnGnnnnanngG 1mdm_AB CCAnGnnnnCnnnTCTCCG |
| Binding Sites: | 1k78_G 1k78_H |
| Publications: | Garvie C. W., Hagman J., Wolberger C. Structural studies of Ets-1/Pax5 complex formation on DNA.. Mol. Cell 8:1267-1276 (2001). [Pubmed] Garvie C.W, Pufall M.A, Graves B.J, Wolberger C. Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships. The Journal of biological chemistry 277:45529-36 (2002). [Pubmed] |
| Related annotations: | PaperBLAST |
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