Transcription Factor

Accessions: T025926_1.02 (CISBP 1.02)
Names: Creb1, T025926_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:bZIP
Length: 327
Pfam Domains: 99-139 pKID domain
267-324 bZIP transcription factor
272-319 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 MTMESGADNQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPN 60
61 GQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSY 120
121 RKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLA 180
181 NNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQI 240
241 RTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENR 300
301 VAVLENQNKTLIEELKALKDLYCHKSD
Interface Residues: 275, 279, 280, 282, 283, 286, 287
3D-footprint Homologues: 7x5e_F, 4eot_A, 1dh3_C, 8k86_A, 5t01_B, 5vpe_D
Binding Motifs: M0297_1.02 rTgACGtmd
Related annotations: PaperBLAST

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