Transcription Factor
| Accessions: | UP00058A (UniPROBE 20160601) |
| Names: | HMG box transcription factor 3, mTCF-3, Tcf3, Tcf7l1, transcription factor 3, Transcription factor 7-like 1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q9Z1J1 |
| Description: | transcription factor 3 |
| Length: | 101 |
| Pfam Domains: | 17-84 HMG (high mobility group) box 18-75 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 AKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSR 60 61 EEQAKYYELARKERQLHAQLYPTWSARDNYGKKKKRKREKQ |
| Interface Residues: | 19, 22, 24, 25, 28, 32, 43, 44, 45, 48, 86, 88, 90, 93 |
| 3D-footprint Homologues: | 2lef_A, 4y60_C, 1j5n_A, 3f27_D, 6jrp_D, 1o4x_B, 3u2b_C, 7m5w_A, 2gzk_A, 4s2q_D, 1hry_A |
| Binding Motifs: | UP00058A_1 twwasATCAAAGgrwww UP00058A_2 rgssgaawawaaaww |
| Binding Sites: | AACATCAA AAGATCAA AATCAAAG ACATCAAA ACTTCAAA ACTTTGAT AGATCAAA AGATCAAT ATCAAAGA ATCAAAGC ATCAAAGG CATCAAAG CCTTTGAA CTTCAAAG CTTTGATA CTTTGATC GAGATCAA GATCAAAA GGATCAAA TGATCAAA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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