Transcription Factor
Accessions: | 2xsd_C (3D-footprint 20231221) |
Names: | Oct-6, Octamer-binding protein 6, Octamer-binding transcription factor 6, OTF-6, PO3F1_MOUSE, POU domain transcription factor SCIP, POU DOMAIN, CLASS 3, TRANSCRIPTION FACTOR 1 |
Organisms: | Mus musculus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P21952 |
Length: | 128 |
Pfam Domains: | 3-73 Pou domain - N-terminal to homeobox domain 82-125 Homeobox domain |
Sequence: (in bold interface residues) | 1 APSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCK 60 61 LKPLLNKWLEETDSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRR 120 121 QKEKRMTP |
Interface Residues: | 25, 41, 42, 43, 44, 46, 47, 53, 57, 67, 71, 110, 111, 113, 114, 117, 118, 121, 122, 125 |
3D-footprint Homologues: | 7u0g_M, 3d1n_M, 1per_L, 3l1p_A, 1o4x_A, 1au7_A, 2xsd_C, 7xrc_C, 8g87_X, 1e3o_C, 3a01_E, 5jlw_D, 2ld5_A, 1le8_A, 1ig7_A, 7q3o_C, 5zjt_E, 3rkq_B, 2r5y_A, 1fjl_B, 5hod_A, 2h1k_B, 6es3_K, 4cyc_A, 1mnm_C, 1b72_A, 7psx_B, 4xrs_G, 1puf_A, 1jgg_B, 5zfz_A, 3lnq_A, 2lkx_A, 1nk2_P, 5flv_I, 3cmy_A, 1zq3_P, 1k61_B |
Binding Motifs: | 2xsd_C CATGCAT |
Binding Sites: | 2xsd_A 2xsd_B |
Publications: | Jauch R, Choo S.H, Ng C.K, Kolatkar P.R. Crystal structure of the dimeric Oct6 (POU3f1) POU domain bound to palindromic MORE DNA. Proteins 79:674-7 (2011). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.