Transcription Factor

						

			
Accessions: Q9UL49 (JASPAR 2024)

			
Names: Cha transcription factor, E2BP-1, HPV-16 E2-binding protein 1, TCFL5_HUMAN, Transcription factor-like 5 protein
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9UL49
Length: 500
Pfam Domains:   401-451 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MSGPGPREPPPEAGAAGGEAAVEGAGGGDAALGEPGLSFTTTDLSLVEMTEVEYTQLQHI   60
  61 LCSHMEAAADGELETRLNSALLAAAGPGAGAGGFAAGGQGGAAPVYPVLCPSALAADAPC  120
 121 LGHIDFQELRMMLLSEAGAAEKTSGGGDGARARADGAAKEGAGAAAAAAGPDGAPEARAK  180
 181 PAVRVRLEDRFNSIPAEPPPAPRGPEPPEPGGALNNLVTLIRHPSELMNVPLQQQNKCTA  240
 241 LVKNKTAATTTALQFTYPLFTTNACSTSGNSNLSQTQSSSNSCSVLEAAKHQDIGLPRAF  300
 301 SFCYQQEIESTKQTLGSRNKVLPEQVWIKVGEAALCKQALKRNRSRMRQLDTNVERRALG  360
 361 EIQNVGEGATATQGAWQSSESSQANLGEQAQSGPQGGRSQRRERHNRMERDRRRRIRICC  420
 421 DELNLLVPFCNAETDKATTLQWTTAFLKYIQERHGDSLKKEFESVFCGKTGRRLKLTRPD  480
 481 SLVTCPAQGSLQSSPSMEIK
Interface Residues: 402, 404, 405, 406, 408, 409, 412, 413, 417, 436
3D-footprint Homologues: 1a0a_B, 1an4_A, 6g1l_A, 7xq5_A, 5eyo_A, 7d8t_A, 4h10_A, 8ia3_B, 5nj8_D, 7ssa_L, 4h10_B, 8osl_O, 5v0l_A, 7xi3_A, 4zpk_A, 2ql2_D, 8osl_P
Binding Motifs: MA0632.2 kCrCGCGCmc
MA0632.3 kCrCGCGC
			
Publications: Siep M, Sleddens-Linkels E, Mulders S, van Eenennaam H, Wassenaar E, Van Cappellen WA, Hoogerbrugge J, Grootegoed JA, Baarends WM. Basic helix-loop-helix transcription factor Tcfl5 interacts with the Calmegin gene promoter in mouse spermatogenesis. Nucleic Acids Res 32:6425-36 (2004). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.