Transcription Factor

Accessions: UP00506A (UniPROBE 20160601)
Names: CG6570, Dmel\CG6570, Ladybird late, Lbl, nkch4
Organisms: Drosophila melanogaster
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: Ladybird late
Length: 138
Pfam Domains: 37-93 Homeobox domain
Sequence:
(in bold interface residues)
1 DTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKY 60
61 LSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKMSANQSFLKNVNDL 120
121 TILKTRPVSRSQSLAPQP
Interface Residues: 36, 37, 38, 39, 40, 78, 79, 81, 82, 85, 86, 89, 90, 93
3D-footprint Homologues: 5zfz_A, 4j19_B, 1puf_A, 3cmy_A, 1fjl_B, 6a8r_A, 3d1n_M, 1ig7_A, 2h1k_B, 1nk2_P, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 5zjt_E, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 1puf_B, 2hos_A, 1b72_A, 5jlw_D, 4cyc_A, 4xrs_G, 3l1p_A, 3a01_E, 6m3d_C, 5flv_I, 1e3o_C, 1le8_A, 2xsd_C, 7xrc_C, 8g87_X, 4qtr_D, 4xrm_B, 1o4x_A, 1du0_A
Binding Motifs: UP00506A_1 amkwgvryyAATTrrcksacyw
Binding Sites: ACCAATTA
ACTAATTA
ATAATTAG
ATAATTGG
CCAATTAA
CCAATTAG
CCCAATTA
CCTAATTA
CCTCATTA
CTAATTAA
CTAATTAG
CTCATTAA
GCCAATTA
GCTAATTA
TAATTAGA
TAATTGGA
TTAATTAA
CCTCGTTA
CCTTGTTA
CTTGTTAA
Publications: Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.