Transcription Factor
| Accessions: | SOX9_HUMAN (HOCOMOCO 10), P48436 (JASPAR 2024) |
| Names: | SOX9_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 509 |
| Pfam Domains: | 22-95 Sox developmental protein N terminal 105-173 HMG (high mobility group) box 106-168 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL 60 61 KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR 120 121 RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK 180 181 SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT 240 241 PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP 300 301 NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP 360 361 QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY 420 421 SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI 480 481 ADTSGVPSIPQTHSPQHWEQPVYTQLTRP |
| Interface Residues: | 107, 110, 112, 113, 116, 120, 131, 132, 133, 136, 174, 178 |
| 3D-footprint Homologues: | 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 6jrp_D, 1qrv_A, 3u2b_C, 7m5w_A, 2gzk_A, 4s2q_D, 1j5n_A, 1hry_A |
| Binding Motifs: | SOX9_HUMAN.H10MO.B|M01522 yCyATTGTTyt MA0077.1 CyATTGTTy MA0077.2 CyATTGTT |
| Binding Sites: | MA0077.2.2 MA0077.1.1 MA0077.1.10 MA0077.1.11 MA0077.1.12 MA0077.1.13 MA0077.1.14 MA0077.1.15 MA0077.1.16 MA0077.1.17 MA0077.1.18 MA0077.1.19 MA0077.1.2 MA0077.1.20 MA0077.1.3 MA0077.1.4 MA0077.1.5 MA0077.1.6 MA0077.1.7 MA0077.1.8 MA0077.1.9 MA0077.2.1 MA0077.2.10 MA0077.2.11 MA0077.2.12 MA0077.2.13 MA0077.2.14 MA0077.2.15 MA0077.2.16 MA0077.2.17 MA0077.2.18 MA0077.2.19 MA0077.2.20 MA0077.2.3 MA0077.2.4 MA0077.2.5 MA0077.2.6 MA0077.2.7 MA0077.2.8 MA0077.2.9 |
| Publications: | Mertin S., McDowall S. G., Harley V. R. The DNA-binding specificity of SOX9 and other SOX proteins. Nucleic Acids Res. 27:1359-1364 (1999). [Pubmed] |
| Related annotations: | PaperBLAST |
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