Transcription Factor

						

			
Accessions: T134498_1.02 (CISBP 1.02)

			
Names: nhr-49, T134498_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 486
Pfam Domains:     19-87 Zinc finger, C4 type (two domains)
  208-391 Ligand-binding domain of nuclear hormone receptor
Sequence: 
(in bold interface residues)		   1 MKNLQMIVIMDLVDPLAEPCAVCGDKSTGTHYGVISCNGCKGFFRRTVLRDQKFTCRFNK   60
  61 RCVIDKNFRCACRYCRFQKCVQVGMKREAIQFERDPVGSPTSGASLNGTPFKKDRSPGYE  120
 121 NGNSNGVGSNGMGQENMRTVPQSSSVIDALMEMEARVNQEMCNRYRRSQIFANGSGGSNG  180
 181 NDTDIQQGSDSGASAFAPPNRPCTTEVDLNEISRTTLLLMVEWAKTINPFMDLSMEDKII  240
 241 LLKNYAPQHLILMPAFRSPDTTRVCLFNNTYMTRDNNTDLNGFAAFKTSNITPRVLDEIV  300
 301 WPMRQLQMREQEFVCLKALAFLHPEAKGLSNSSQIMIRDARNRVLKALYAFILDQMPDDA  360
 361 PTRYGNILLLAPALKALTQLLIENMTLTKFFGLAEVDSLLSEFILDDINDHSTAPVSLQQ  420
 421 HLSSPTTLPTNGVSPLNPAGSVGSVSSVSGITPTGMLSATLAAPLAIHPLQSQDSILNSE  480
 481 QNNHML
Interface Residues: 28, 29, 31, 32, 38, 39, 41, 42, 45, 46, 70, 92, 94, 96, 101, 104, 113, 115
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 8hbm_B, 5krb_G, 2han_A, 1hcq_E, 2han_B, 1kb2_B, 7xv6_B, 2a66_A, 4umm_E, 2nll_B, 1lat_A, 8cef_H, 2ff0_A, 1dsz_A, 3cbb_A, 5cbz_E, 3g6t_A, 1r4i_A, 4tnt_B, 5e69_A, 5emc_A, 4hn5_B, 7prw_B, 5cbx_B
Binding Motifs: M1474_1.02 kTgrwchsd
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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