Transcription Factor

Accessions: 5vpe_C (3D-footprint 20231221)
Names: FOSB_HUMAN, G0/G1 switch regulatory protein 3, Protein fosB
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P53539
Length: 66
Pfam Domains: 1-59 bZIP transcription factor
3-55 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 EEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLE 60
61 FVLVAH
Interface Residues: 9, 10, 13, 14, 16, 17, 20, 21, 24
3D-footprint Homologues: 7x5e_E, 1skn_P, 5vpe_C, 7x5e_F, 2wt7_A, 6mg1_B, 1nwq_C, 5t01_B, 5vpe_D, 4eot_A
Binding Motifs: 5vpe_C aGTcACc
Binding Sites: 5vpe_G
5vpe_H
Publications: Yin Z, Machius M, Nestler EJ, Rudenko G. Activator Protein-1: redox switch controlling structure and DNA-binding. Nucleic Acids Res 45:11425-11436 (2017). [Pubmed]
Related annotations: PaperBLAST

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