Transcription Factor

Accessions: KLF13_full (HumanTF 1.0)
Names: Basic transcription element-binding protein 3, BTE-binding protein 3, KLF13, KLF13_HUMAN, Krueppel-like factor 13, Novel Sp1-like zinc finger transcription factor 1, RANTES factor of late activated T-lymphocytes 1, RFLAT-1, Transcription factor BTEB3, Transcription factor NSLP1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q9Y2Y9
Notes: Ensembl ID: ENSG00000169926; Full protein sequence; TF family: znfC2H2; Clone source: hORFeome
Length: 289
Pfam Domains: 167-191 C2H2-type zinc finger
167-191 Zinc finger, C2H2 type
183-209 Zinc-finger double domain
197-221 Zinc finger, C2H2 type
197-221 C2H2-type zinc finger
214-236 Zinc-finger double domain
227-249 Zinc finger, C2H2 type
227-249 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MAAAAYVDHFAAECLVSMSSRAVVHGPREGPESRPEGAAVAATPTLPRVEERRDGKDSAS 60
61 LFVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPPPAPEPTSPGAEGAAAAPPSP 120
121 AWSEPEPEAGLEPEREPGPAGSGEPGLRQRVRRGRSRADLESPQRKHKCHYAGCEKVYGK 180
181 SSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSD 240
241 HLTKHARRHANFHPGMLQRRGGGSRTGSLSDYSRSDASSPTISPASSP*
Interface Residues: 141, 142, 144, 152, 156, 175, 179, 180, 181, 182, 183, 185, 186, 188, 189, 192, 208, 209, 210, 211, 212, 213, 215, 216, 217, 220, 237, 238, 239, 240, 241, 242, 243, 244, 245, 247, 248
3D-footprint Homologues: 8ssq_A, 7w1m_H, 8ssu_A, 5kkq_D, 7n5w_A, 6jnm_A, 3uk3_C, 1tf3_A, 8cuc_F, 5ei9_F, 1g2f_F, 5kl3_A, 1ubd_C, 2kmk_A, 7ysf_A, 6ml4_A, 6blw_A, 5k5l_F, 6u9q_A, 4x9j_A, 2gli_A, 1tf6_A, 8h9h_G, 7y3m_I, 2lt7_A, 6e94_A, 6a57_A, 2jpa_A, 8gn3_A, 7y3l_A, 7txc_E, 5k5i_A, 1llm_D, 2drp_D, 1f2i_J, 2wbs_A, 4m9v_C, 5yel_A, 5yj3_D, 5v3j_F
Binding Motifs: KLF13_full rtRmCACGCCCCYTTttg
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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