Transcription Factor

						

			
Accessions: UP00052A (UniPROBE 20160601)

			
Names: odd-skipped related 2 (Drosophila), Osr2, Protein odd-skipped-related 2
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q91ZD1
Description: odd-skipped related 2 (Drosophila): odd-skipped related 2 (Drosophila) (Osr2), mRNA
Length: 109
Pfam Domains:     16-38 C2H2-type zinc finger
    16-38 Zinc finger, C2H2 type
    16-33 C2H2-type zinc finger
    30-54 Zinc-finger double domain
    43-64 C2H2-type zinc finger
    44-66 C2H2-type zinc finger
    44-66 Zinc finger, C2H2 type
    58-81 Zinc-finger double domain
    72-91 C2H2-type zinc finger
    72-94 Zinc finger, C2H2 type
    72-96 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 RKPSRGRLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLR   60
  61 DHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQTSSPTAASSAAKC
Interface Residues: 16, 26, 27, 28, 29, 30, 32, 33, 34, 39, 40, 41, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 65, 82, 83, 84, 85, 86, 87, 89
3D-footprint Homologues: 2kmk_A, 7n5w_A, 1tf3_A, 6jnm_A, 3uk3_C, 8cuc_F, 7y3l_A, 6ml4_A, 2gli_A, 1llm_D, 6blw_A, 5kkq_D, 1ubd_C, 6u9q_A, 4x9j_A, 2i13_A, 1mey_C, 5kl3_A, 6wmi_A, 5ei9_F, 2jpa_A, 5und_A, 2drp_D, 1g2f_F, 5k5i_A, 1tf6_A, 8h9h_G, 7eyi_G, 4m9v_C, 8gh6_A, 2lt7_A, 7y3m_I, 6e94_A, 7ysf_A, 6a57_A, 7w1m_H, 1yuj_A, 5yel_A, 8gn3_A, 7txc_E, 2wbs_A, 1f2i_J, 5yj3_D, 8ssq_A, 5v3j_F
Binding Motifs: UP00052A_1 wwrwACrGTAGCwmwr
UP00052A_2 rhttGCTACywrmwym
Binding Sites: AACAGTAG
ACAGAAGC
ACAGTAGT
ACGGTAGC
AGCTACCG
AGCTACTG
AGTAGCTA
CAGTAGCA
CAGTAGCC
CAGTAGCG
CCAGTAGC
CCGGTAGC
CGCTACCG
CGGTAGCA
CGGTAGCC
CTACTGTA
GCAGTAGC
GCTACCGA
GCTACTGA
GTAGCTAC
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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