Transcription Factor

Accessions: Q15697 (JASPAR 2024)
Names: AW-1, Zinc finger and SCAN domain-containing protein 8, Zinc finger protein 174, ZN174_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q15697
Length: 407
Pfam Domains: 41-135 SCAN domain
323-336 Zinc-finger double domain
326-348 C2H2-type zinc finger
326-348 Zinc finger, C2H2 type
341-364 Zinc-finger double domain
354-376 Zinc finger, C2H2 type
369-392 Zinc-finger double domain
382-405 C2H2-type zinc finger
382-404 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MAAKMEITLSSNTEASSKQERHIIAKLEEKRGPPLQKNCPDPELCRQSFRRFCYQEVSGP 60
61 QEALSQLRQLCRQWLQPELHTKEQILELLVMEQFLTILPPEIQARVRHRCPMSSKEIVTL 120
121 VEDFHRASKKPKQWVAVCMQGQKVLLEKTGSQLGEQELPDFQPQTPRRDLRESSPAEPSQ 180
181 AGAYDRLSPHHWEKSPLLQEPTPKLAGTEAPRMRSDNKENPQQEGAKGAKPCAVSAGRSK 240
241 GNGLQNPEPRGANMSEPRLSRRQVSSPNAQKPFAHYQRHCRVEYISSPLKSHPLRELKKS 300
301 KGGKRSLSNRLQHLGHQPTRSAKKPYKCDDCGKSFTWNSELKRHKRVHTGERPYTCGECG 360
361 NCFGRQSTLKLHQRIHTGEKPYQCGQCGKSFRQSSNLHQHHRLHHGD
Interface Residues: 309, 311, 312, 313, 315, 317, 318, 321, 326, 336, 337, 338, 339, 340, 342, 343, 344, 346, 347, 364, 365, 366, 367, 368, 369, 370, 371, 372, 378, 379, 392, 393, 394, 395, 396, 398, 399, 403
3D-footprint Homologues: 5ei9_F, 2i13_A, 1tf6_A, 2jpa_A, 2kmk_A, 1tf3_A, 6jnm_A, 8cuc_F, 7y3l_A, 6ml4_A, 7n5w_A, 1mey_C, 5kl3_A, 7ysf_A, 1f2i_J, 6wmi_A, 8ssq_A, 7w1m_H, 5und_A, 2drp_D, 1g2f_F, 7eyi_G, 5k5i_A, 8ssu_A, 2gli_A, 8gn3_A, 1llm_D, 6blw_A, 5kkq_D, 1ubd_C, 6u9q_A, 5yel_A, 4x9j_A, 5v3j_F, 4m9v_C, 8h9h_G, 6e94_A, 2lt7_A, 7y3m_I, 6a57_A, 3uk3_C, 7txc_E, 2wbs_A, 5yj3_D, 1yuj_A
Binding Motifs: UN0164.1 kGsCrrTCACTyGcCa
UN0164.2 GsCrrTCACTyGcC
Related annotations: PaperBLAST

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