Transcription Factor

						

			
Accessions: 5nj8_D (3D-footprint 20231221)

			
Names: ARNT protein, ARNT_HUMAN, Aryl hydrocarbon receptor nuclear translocator, bHLHe2, Class E basic helix-loop-helix protein 2, Dioxin receptor, nuclear translocator, HIF-1-beta, HIF1-beta, Hypoxia-inducible factor 1-beta
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P27540
Length: 134
Pfam Domains:      8-60 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 ADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLR   60
  61 GTSTDGSYKPSFLTDQELKHLILEAADFLFYVSDSVTPVQPQSESTLYDSRRSFICRMRC  120
 121 HCTGYIKALVAIGR
Interface Residues: 8, 10, 11, 12, 14, 15, 18, 19, 43, 45, 105
3D-footprint Homologues: 1a0a_B, 1an4_A, 1am9_A, 5nj8_D, 4zpk_A, 7d8t_A, 5gnj_I, 7xi3_A, 5v0l_A, 4zpk_B, 7rcu_E, 5i50_B, 4h10_A, 4zpr_B, 7ssa_L, 4h10_B, 6g1l_A, 5eyo_A, 8osl_P, 8osl_O, 5nj8_C, 5v0l_B, 7vw3_A
Binding Motifs: 5nj8_D CgTGA
Binding Sites: 5nj8_G
5nj8_H
			
Publications: Schulte KW, Green E, Wilz A, Platten M, Daumke O. Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation. Structure 25:1025-1033 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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