Transcription Factor
| Accessions: | 1hcq_B (3D-footprint 20231221) |
| Names: | ER, ER-alpha, ESR1_HUMAN, Estradiol receptor, ESTROGEN RECEPTOR, Nuclear receptor subfamily 3 group A member 1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P03372 |
| Length: | 71 |
| Pfam Domains: | 3-71 Zinc finger, C4 type (two domains) |
| Sequence: (in bold interface residues) | 1 TRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACR 60 61 LRKCYEVGMMK |
| Interface Residues: | 12, 13, 15, 16, 22, 23, 25, 26, 29, 30, 54 |
| 3D-footprint Homologues: | 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B |
| Binding Motifs: | 1hcq_AB GGTCAnnntGaCC |
| Binding Sites: | 1hcq_C 1hcq_D |
| Publications: | Schwabe J. W. R., Chapman L., Finch J. T., Rhodes D. The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements. Cell 75:567-578 (1993). [Pubmed] |
| Related annotations: | PaperBLAST |
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