Transcription Factor
| Accessions: | UP00097A (UniPROBE 20160601) |
| Names: | metal response element binding transcription factor 1, metal response element-binding transcription factor 1, Metal-regulatory transcription factor 1, metalloregulatory transcription factor, MRE-binding transcription factor, Mtf-1, Mtf1, Transcription factor MTF-1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q07243 |
| Description: | metal response element binding transcription factor 1: Metal response element binding transcription factor 1 |
| Length: | 204 |
| Pfam Domains: | 16-40 C2H2-type zinc finger 16-40 Zinc finger, C2H2 type 32-59 Zinc-finger double domain 46-70 Zinc finger, C2H2 type 46-70 C2H2-type zinc finger 62-89 Zinc-finger double domain 76-100 Zinc finger, C2H2 type 76-100 C2H2-type zinc finger 93-118 Zinc-finger double domain 105-129 Zinc finger, C2H2 type 105-129 C2H2-type zinc finger 121-147 Zinc-finger double domain 135-159 Zinc finger, C2H2 type 135-159 C2H2-type zinc finger 151-178 Zinc-finger double domain 165-189 Zinc finger, C2H2 type 167-189 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 LQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTS 60 61 YSLRIHVRVHTKEKPFECDVRGCEKAFNTLYRLKAHQRLHTGKTFNCESQGCSKYFTTLS 120 121 DLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQY 180 181 SLKSHMKGHDNKGTAYSALPQHNG |
| Interface Residues: | 29, 31, 32, 35, 58, 59, 60, 61, 62, 64, 65, 67, 68, 69, 71, 84, 86, 87, 89, 90, 91, 92, 93, 94, 95, 96, 99, 116, 117, 118, 119, 120, 121, 123, 124, 128, 140, 147, 148, 149, 150, 151, 153, 154, 155, 158, 177, 178, 179, 180, 181, 182, 183, 184, 185 |
| 3D-footprint Homologues: | 8ssu_A, 2i13_A, 6wmi_A, 8ssq_A, 7w1m_H, 5v3j_F, 6jnm_A, 5kkq_D, 1tf6_A, 5ei9_F, 2kmk_A, 6e94_A, 6a57_A, 2jpa_A, 5yel_A, 6ml4_A, 1g2f_F, 5k5i_A, 1mey_C, 2gli_A, 7eyi_G, 7ysf_A, 6dg0_A, 1ubd_C, 1tf3_A, 7y3l_A, 7n5w_A, 8cuc_F, 6blw_A, 4x9j_A, 5kl3_A, 6u9q_A, 1llm_D, 7txc_E, 5und_A, 1f2i_J, 8h9h_G, 2lt7_A, 7y3m_I, 8gn3_A, 3uk3_C, 2wbs_A, 4m9v_C, 5yj3_D |
| Binding Motifs: | UP00097A_1 kggyCGTGYGCAamdh UP00097A_2 aaatawgAAawawv |
| Binding Sites: | ACCCCGCC AGTGCAAA AGTGTGCA CGAGTGCA CGCGTGCA CGGGTGCA CGTGCGCA CGTGTGAA CTGCACAC GAGTGCAA GGGTGCAA GGTGCAAA GTGCAAAA GTGCACAC GTGCGCAA GTGCGCAC GTGTGCAA TGCGCACA TGTGCACA CGGGCGCA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.