Transcription Factor
| Accessions: | UP00097A (UniPROBE 20160601) |
| Names: | metal response element binding transcription factor 1, metal response element-binding transcription factor 1, Metal-regulatory transcription factor 1, metalloregulatory transcription factor, MRE-binding transcription factor, Mtf-1, Mtf1, Transcription factor MTF-1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q07243 |
| Description: | metal response element binding transcription factor 1: Metal response element binding transcription factor 1 |
| Length: | 204 |
| Pfam Domains: | 16-40 Zinc finger, C2H2 type 16-40 C2H2-type zinc finger 32-59 Zinc-finger double domain 46-70 Zinc finger, C2H2 type 46-70 C2H2-type zinc finger 62-89 Zinc-finger double domain 76-100 C2H2-type zinc finger 76-100 Zinc finger, C2H2 type 93-118 Zinc-finger double domain 105-129 C2H2-type zinc finger 105-129 Zinc finger, C2H2 type 121-147 Zinc-finger double domain 135-159 C2H2-type zinc finger 135-159 Zinc finger, C2H2 type 151-178 Zinc-finger double domain 165-189 Zinc finger, C2H2 type 167-189 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 LQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTS 60 61 YSLRIHVRVHTKEKPFECDVRGCEKAFNTLYRLKAHQRLHTGKTFNCESQGCSKYFTTLS 120 121 DLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQY 180 181 SLKSHMKGHDNKGTAYSALPQHNG |
| Interface Residues: | 29, 31, 32, 35, 58, 59, 60, 61, 62, 64, 65, 67, 68, 69, 71, 84, 86, 87, 89, 90, 91, 92, 93, 94, 95, 96, 99, 116, 117, 118, 119, 120, 121, 123, 124, 128, 140, 147, 148, 149, 150, 151, 153, 154, 155, 158, 177, 178, 179, 180, 181, 182, 183, 184, 185 |
| 3D-footprint Homologues: | 6wmi_A, 8ssq_A, 7w1m_H, 5v3j_F, 8ssu_A, 2i13_A, 6jnm_A, 2kmk_A, 5kkq_D, 1tf6_A, 5ei9_F, 6e94_A, 6a57_A, 2jpa_A, 5yel_A, 5k5i_A, 1mey_C, 2gli_A, 6ml4_A, 1g2f_F, 7eyi_G, 7ysf_A, 6dg0_A, 1ubd_C, 8cuc_F, 1tf3_A, 7y3l_A, 7n5w_A, 1llm_D, 7txc_E, 5und_A, 1f2i_J, 6blw_A, 4x9j_A, 5kl3_A, 6u9q_A, 8h9h_G, 2lt7_A, 7y3m_I, 8gn3_A, 3uk3_C, 2wbs_A, 4m9v_C, 5yj3_D |
| Binding Motifs: | UP00097A_1 kggyCGTGYGCAamdh UP00097A_2 aaatawgAAawawv |
| Binding Sites: | ACCCCGCC AGTGCAAA AGTGTGCA CGAGTGCA CGCGTGCA CGGGTGCA CGTGCGCA CGTGTGAA CTGCACAC GAGTGCAA GGGTGCAA GGTGCAAA GTGCAAAA GTGCACAC GTGCGCAA GTGCGCAC GTGTGCAA TGCGCACA TGTGCACA CGGGCGCA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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