Transcription Factor

						

			
Accessions: T093256_1.02 (CISBP 1.02)

			
Names: LHX2, T093256_1.02;
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Homeodomain
Length: 412
Pfam Domains:    51-105 LIM domain
  121-176 LIM domain
  263-325 Homeobox KN domain
  273-329 Homeobox domain
Sequence: 
(in bold interface residues)		   1 XHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKISD   60
  61 RYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYSPSLHGPYRRFSVQR  120
 121 CARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQ  180
 181 GEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPG  240
 241 ADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAK  300
 301 DLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPASELS  360
 361 NASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF
Interface Residues: 272, 273, 274, 275, 276, 314, 315, 317, 318, 321, 322, 324, 325, 326, 328, 329, 339, 342
3D-footprint Homologues: 3d1n_M, 1fjl_B, 5zfz_A, 8ejp_B, 1ig7_A, 6fqp_B, 8pmf_A, 1puf_A, 6a8r_A, 3cmy_A, 2r5y_A, 1zq3_P, 3lnq_A, 1nk2_P, 1jgg_B, 2lkx_A, 6m3d_C, 6es3_K, 2ld5_A, 7q3o_C, 9b8u_A, 1puf_B, 4xrs_G, 2hos_A, 8ik5_C, 7psx_B, 1b72_A, 4j19_B, 5flv_I, 8osb_E, 5zjt_E, 3a01_E, 2d5v_B, 8eml_B, 5hod_A, 3rkq_B, 2hdd_A, 5jlw_D, 4cyc_A, 2xsd_C, 7xrc_C, 1e3o_C, 1le8_A, 8bx1_A, 1le8_B, 1du0_A, 4qtr_D, 6fqq_E, 8g87_X, 4xrm_B
Binding Motifs: M0889_1.02 yryyAatkar
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.