Transcription Factor

Accessions: UP00011A (UniPROBE 20160601)
Names: AI876454, E230028I05Rik, interferon regulatory factor 6, Irf6, mirf6
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q8C2Z7
Description: interferon regulatory factor 6
Length: 132
Pfam Domains: 6-114 Interferon regulatory factor transcription factor
Sequence:
(in bold interface residues)
1 ALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWA 60
61 VETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQVCDIPQTQG 120
121 SVINPGSTGSAP
Interface Residues: 41, 43, 76, 80, 81, 83, 84, 87, 88
3D-footprint Homologues: 2o61_A, 2pi0_B, 1if1_B, 2irf_L, 7oot_B
Binding Motifs: UP00011A_1 mwdayCGAWACyaaakw
UP00011A_2 mbywcTCyCGgkcrs
Binding Sites: AACGAAAC
ACCGAAAC
ACCGATAC
ACGAAACC
AGTATCGG
AGTTTCGA
AGTTTCGG
ATCGAAAC
ATCGATAC
CAGTTTCG
CCGAAACC
CCGATACC
CGAAACCA
CGAAACCG
CGAAACTA
CGAAACTC
CGATACCA
CGATACTA
GGTATCGA
GGTTTCGA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.