Transcription Factor
| Accessions: | UP00222A (UniPROBE 20160601) |
| Names: | AI385728, AI987804, Hepatocyte nuclear factor 1-beta, hepatocyte nuclear factor-1 beta, Hnf-1b, HNF-1beta, Hnf1b, Hnf1beta, Homeoprotein LFB3, Tcf-2, Tcf2, transcription factor 2, Variant hepatic nuclear factor 1, vHNF1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P27889 |
| Description: | transcription factor 2: TCF2 gene, VIRTUAL TRANSCRIPT, partial sequence, genomic survey sequence |
| Length: | 114 |
| Pfam Domains: | 17-90 Homeobox domain |
| Sequence: (in bold interface residues) | 1 PGQSEDTCSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQ 60 61 RGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDACSSNQTHNLNPL |
| Interface Residues: | 17, 20, 80, 81, 82, 83, 86, 87, 90 |
| 3D-footprint Homologues: | 5zfz_A, 1fjl_B, 1ic8_B, 4j19_B, 2h8r_B, 1le8_A, 7q3o_C, 3cmy_A, 5zjt_E, 3rkq_B |
| Binding Motifs: | UP00222A_1 dkykGTTAACTAryybt |
| Binding Sites: | AACTAACC ACTAACTA ACTAGTTA AGGTTAAC AGTTAACC AGTTAACT ATAACTAG ATTAACTA CGGTTAAC CTAACTAG CTAGTTAA CTGGTTAA CTTAACTA GGTTAACC GTAGTTAA GTTAACCA GTTAGTTA TAACTAGA TTAACCAA TTAACTAA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.