Transcription Factor
| Accessions: | ELK3 (HT-SELEX2 May2017) |
| Names: | ELK3, ENSG00000111145 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: ETS experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: ETS experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2 |
| Length: | 107 |
| Pfam Domains: | 3-84 Ets-domain |
| Sequence: (in bold interface residues) | 1 SAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRA 60 61 LRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQD |
| Interface Residues: | 55, 56, 58, 59, 60, 62, 63, 77 |
| 3D-footprint Homologues: | 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A |
| Binding Motifs: | ELK3_2 rrCCGGAAGtr ELK3_3 sTCGTAAATgCa ELK3_5 rCCGGAAGTr ELK3_6 CTCGTAAATGCa ELK3_methyl_1 rrCCGGAAGtg ELK3_methyl_4 rrCCGGAAGtr |
| Related annotations: | PaperBLAST |
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