Transcription Factor

Accessions: UP00162A (UniPROBE 20160601)
Names: even skipped homeotic gene 1 homolog, EVX-1, Evx1, Homeobox even-skipped homolog protein 1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P23683
Description: even skipped homeotic gene 1 homolog
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 GSGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTI 60
61 KVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMM
Interface Residues: 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 73
3D-footprint Homologues: 1puf_A, 1ig7_A, 3cmy_A, 5zfz_A, 3d1n_M, 1fjl_B, 6a8r_A, 2h1k_B, 2lkx_A, 1jgg_B, 6m3d_C, 1nk2_P, 1zq3_P, 3lnq_A, 6es3_K, 2ld5_A, 7q3o_C, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1puf_B, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 3l1p_A, 3a01_E, 1b72_A, 5jlw_D, 7xrc_C, 1e3o_C, 2xsd_C, 1au7_A, 1le8_A, 1mnm_C, 1du0_A, 8g87_X, 1k61_B, 1o4x_A, 4qtr_D
Binding Motifs: UP00162A_1 wvarcTAATTAgygswc
Binding Sites: GGTAATTA
AATAATTA
ACTAATTA
AGTAATTA
ATAATTAC
ATAATTAG
ATTAATTA
CCTAATTA
CGTAATTA
CTAATTAA
CTAATTAC
CTTAATTA
GATAATTA
GCTAATTA
GTAATTAA
GTAATTAC
GTTAATTA
TAATTACA
TAATTAGA
TTAATTAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.