Transcription Factor

Accessions: HOXD9 (HT-SELEX2 May2017)
Names: ENSG00000128709, HOXD9
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: Homeodomain experiment: HT-SELEX Hamming distance: 1 cycle: 4, TF family: Homeodomain experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 4
Length: 110
Pfam Domains: 44-100 Homeobox domain
Sequence:
(in bold interface residues)
1 SACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPEANWIHARSTRKKRCPYTKYQTLELEK 60
61 EFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD
Interface Residues: 44, 45, 46, 47, 85, 86, 88, 89, 92, 93, 96, 97, 100
3D-footprint Homologues: 1ig7_A, 6a8r_A, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 6m3d_C, 3d1n_M, 1zq3_P, 2lkx_A, 1nk2_P, 2ld5_A, 7q3o_C, 6es3_K, 7psx_B, 3a01_E, 1jgg_B, 5jlw_D, 3lnq_A, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1puf_B, 5flv_I, 2hos_A, 1b72_A, 5zjt_E, 4cyc_A, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 1au7_A, 5hod_A, 3l1p_A, 1o4x_A, 1du0_A, 4qtr_D, 8g87_X
Binding Motifs: HOXD9_3 GymATAAAAm
HOXD9_4 rTCRTAAAah
HOXD9_7 gTCGTAAAay
HOXD9_8 GymATAAAAh
HOXD9_methyl_1 RTCGTAAAac
HOXD9_methyl_2 GymATwAAac
HOXD9_methyl_5 rTCGTAAAay
HOXD9_methyl_6 GymATWAAac
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.