Transcription Factor
| Accessions: | ftz (DrosophilaTF 1.1), P02835 (JASPAR 2024) |
| Names: | FTZ_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P02835 |
| Length: | 410 |
| Pfam Domains: | 1-248 Fushi tarazu (FTZ), N-terminal region 255-311 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MATTNSQSHYSYADNMNMYNMYHPHSLPPTYYDNSGSNAYYQNTSNYQGYYPQESYSESC 60 61 YYYNNQEQVTTQTVPPVQPTTPPPKATKRKAEDDAASIIAAVEERPSTLRALLTNPVKKL 120 121 KYTPDYFYTTVEQVKKAPAVSTKVTASPAPSYDQEYVTVPTPSASEDVDYLDVYSPQSQT 180 181 QKLKNGDFATPPPTTPTSLPPLEGISTPPQSPGEKSSSAVSQEINHRIVTAPNGAGDFNW 240 241 SHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKI 300 301 WFQNRRMKSKKDRTLDSSPEHCGAGYTAMLPPLEATSTATTGAPSVPVPMYHHHQTTAAY 360 361 PAYSHSHSHGYGLLNDYPQQQTHQQYDAYPQQYQHQCSYQQHPQDLYHLS |
| Interface Residues: | 239, 255, 256, 257, 258, 259, 296, 297, 299, 300, 303, 304, 307, 308, 311 |
| 3D-footprint Homologues: | 1e3o_C, 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 1fjl_B, 1ig7_A, 6a8r_A, 2lkx_A, 1jgg_B, 6m3d_C, 1zq3_P, 3lnq_A, 7q3o_C, 6es3_K, 1nk2_P, 2ld5_A, 3a01_E, 5jlw_D, 3rkq_B, 4xrs_G, 2hdd_A, 4cyc_A, 2r5y_A, 1puf_B, 1au7_A, 5flv_I, 2hos_A, 5zjt_E, 4j19_B, 7psx_B, 1b72_A, 7xrc_C, 2xsd_C, 1le8_A, 1le8_B, 1du0_A, 1mnm_C, 1k61_B, 3l1p_A, 8g87_X, 5hod_A, 1o4x_A, 4qtr_D |
| Binding Motifs: | MA0225.1 TTAATkA ftz rcryTAATGrcmt |
| Binding Sites: | MA0225.1.20 MA0225.1.10 MA0225.1.15 MA0225.1.3 MA0225.1.1 MA0225.1.11 MA0225.1.12 MA0225.1.13 MA0225.1.14 MA0225.1.16 MA0225.1.17 MA0225.1.18 MA0225.1.19 MA0225.1.2 MA0225.1.4 MA0225.1.5 MA0225.1.6 MA0225.1.7 MA0225.1.8 MA0225.1.9 |
| Publications: | Wilson D.S, Sheng G, Jun S, Desplan C. Conservation and diversification in homeodomain-DNA interactions: a comparative genetic analysis. Proceedings of the National Academy of Sciences of the United States of America 93:6886-91 (1996). [Pubmed] Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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