Transcription Factor
| Accessions: | P15173 (JASPAR 2024) |
| Names: | bHLHc3, Class C basic helix-loop-helix protein 3, Myf-4, MYOG_HUMAN, Myogenic factor 4, Myogenin |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 224 |
| Pfam Domains: | 1-81 Myogenic Basic domain 82-133 Helix-loop-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MELYETSPYFYQEPRFYDGENYLPVHLQGFEPPGYERTELTLSPEAPGPLEDKGLGTPEH 60 61 CPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVE 120 121 ILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPGVPSECSSHSASCSPEWGSALEFS 180 181 ANPGDHLLTADPTDAHNLHSLTSIVDSITVEDVSVAFPDETMPN |
| Interface Residues: | 83, 86, 87, 89, 90, 91, 93, 94 |
| 3D-footprint Homologues: | 7z5k_B, 2ypa_A, 6od3_F, 4h10_A, 5i50_B, 1am9_A, 2ql2_A, 2ql2_D, 8osl_P, 6g1l_A, 2ypa_B |
| Binding Motifs: | MA0500.2 sarCAGCTGyts MA0500.3 rCAGCTGy |
| Binding Sites: | MA0500.3.17 MA0500.3.1 / MA0500.3.6 MA0500.3.19 MA0500.3.13 / MA0500.3.16 / MA0500.3.9 MA0500.3.11 / MA0500.3.12 MA0500.2.1 MA0500.2.10 MA0500.2.11 MA0500.2.12 MA0500.2.13 MA0500.2.14 MA0500.2.15 MA0500.2.16 MA0500.2.15 / MA0500.2.17 MA0500.2.16 / MA0500.2.18 MA0500.2.17 / MA0500.2.19 MA0500.2.2 MA0500.2.18 / MA0500.2.20 MA0500.2.3 / MA0500.2.5 MA0500.2.4 / MA0500.2.6 MA0500.2.5 MA0500.2.6 MA0500.2.7 MA0500.2.8 MA0500.2.9 MA0500.2.19 MA0500.2.20 MA0500.2.3 MA0500.2.4 MA0500.3.10 / MA0500.3.14 / MA0500.3.15 MA0500.3.18 MA0500.3.2 / MA0500.3.5 MA0500.3.20 MA0500.3.3 MA0500.3.4 MA0500.3.7 MA0500.3.8 |
| Publications: | Cao Y, Kumar R.M, Penn B.H, Berkes C.A, Kooperberg C, Boyer L.A, Young R.A, Tapscott S.J. Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters. The EMBO journal 25:502-11 (2006). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.