Transcription Factor

						

			
Accessions: 4s0h_E (3D-footprint 20231221)

			
Names: T-box protein 5, T-box transcription factor TBX5, TBX5_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q99593
Length: 177
Pfam Domains:     4-176 T-box
Sequence: 
(in bold interface residues)		   1 GIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDH   60
  61 RYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHII  120
 121 LNSMHKYQPRLHIVKADTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRG
Interface Residues: 29, 154, 155, 171, 174, 175
3D-footprint Homologues: 5flv_I, 1xbr_B, 6f59_B, 2x6v_A, 4a04_B, 1h6f_B
Binding Motifs: 4s0h_EF CACnnnnnAAGTG
			
Publications: Pradhan L, Gopal S, Li S, Ashur S, Suryanarayanan S, Kasahara H, Nam HJ. Intermolecular Interactions of Cardiac Transcription Factors NKX2. 5 and TBX5 55:1702-10 (Biochemistry.). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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