Transcription Factor

Accessions: UP00579A (UniPROBE 20160601)
Names: ANAC105, Arabidopsis NAC domain containing protein 105, K1L20_8, K1L20.8, NAC domain containing protein, VASCULAR-RELATED NAC-DOMAIN 3, VND3
Organisms: Arabidopsis thaliana
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: NAC domain containing protein: Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, ge
Length: 165
Pfam Domains: 13-139 No apical meristem (NAM) protein
Sequence:
(in bold interface residues)
1 MMKVDQDYSCSIPPGFRFHPTDEELVGYYLKKKIASQRIDLDVIREIDLYKIEPWDLQER 60
61 CRIGYEEQTEWYFFSHRDKKYPTGTRTNRATVAGFWKATGRDKAVYLNSKLIGMRKTLVF 120
121 YRGRAPNGQKSDWIIHEYYSLESHQNSPPQEEGWVVCRAFKKRTT
Interface Residues: 81, 86, 88, 97, 99, 101, 121, 125, 126, 127, 130
3D-footprint Homologues: 7xp3_B, 3swp_A
Binding Motifs: UP00579A_1 wrCACGGmACyt
UP00579A_2 gtACACGsAACy
Binding Sites: ACGGAACC
ATACGTAA
ATTCCGTG
CACGGCAC
GTTACGTA
TTACGTAA
ACACGCAA
ACACGGAA
ACACGGCA
ACACGTAA
ACACGTCA
ACGCAACT
ACGGCACT
ACGTAACT
CACGCAAC
CACGGAAC
CACGTAAC
GCACGGAA
GCACGGCA
GTTCCGTA
Publications: Lindemose S, Jensen MK, Van de Velde J, O'Shea C, Heyndrickx KS, Workman CT, Vandepoele K, Skriver K, De Masi F. A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana. Nucleic Acids Res 42:7681-93 (2014). [Pubmed]
Related annotations: PaperBLAST

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