Transcription Factor
| Accessions: | ems (DrosophilaTF 1.1), P18488 (JASPAR 2024) |
| Names: | EMS_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | DrosophilaTF 1.1 1, JASPAR 2024 2 1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 497 |
| Pfam Domains: | 392-448 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MTKMIPPVPTAAAAVMMPTPKQKIGFSIESIVGNDVSTAGGNSTPDLSGPQSPPPGERNV 60 61 PGSPPQTPPATLTLIPGSPPHHLMAPPAHGLPYPHPHAQQQQQQHLQAPHPHPHLSPAQQ 120 121 HVLHQHLLMQHQHPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSL 180 181 KRERSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQ 240 241 PPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYIN 300 301 APPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDS 360 361 YQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAE 420 421 RKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGDEDDDELIDM 480 481 EMDECPSDEEHELDASH |
| Interface Residues: | 389, 391, 392, 393, 394, 395, 433, 434, 436, 437, 440, 441, 444, 445, 448 |
| 3D-footprint Homologues: | 1ig7_A, 3d1n_M, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1nk2_P, 1fjl_B, 5zfz_A, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 1zq3_P, 6es3_K, 7q3o_C, 2ld5_A, 3a01_E, 5hod_A, 2hdd_A, 7psx_B, 5jlw_D, 3rkq_B, 2r5y_A, 1au7_A, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 3l1p_A, 5zjt_E, 1e3o_C, 2xsd_C, 1le8_A, 7xrc_C, 1le8_B, 1du0_A, 8g87_X, 4qtr_D, 1mnm_C, 1puf_B, 1k61_B, 6fqp_B, 1o4x_A, 4j19_B |
| Binding Motifs: | MA0219.1 yTAATkR ems AAnTnTAATGACA |
| Binding Sites: | MA0219.1.18 MA0219.1.20 MA0219.1.14 MA0219.1.1 MA0219.1.10 MA0219.1.11 MA0219.1.12 MA0219.1.13 MA0219.1.15 MA0219.1.16 MA0219.1.17 MA0219.1.19 MA0219.1.2 MA0219.1.3 MA0219.1.4 MA0219.1.5 MA0219.1.6 MA0219.1.7 MA0219.1.8 MA0219.1.9 |
| Publications: | Taylor H. S. A regulatory element of the spiracles homeobox gene is composed of three distinct conserved regions that bind regulatory proteins.. Mol. Reprod. Dev. 49:246-253 (1998). [Pubmed] Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.