Transcription Factor

						

			
Accessions: TBX20_full (HumanTF 1.0)

			
Names: T-box protein 20, T-box transcription factor TBX20, TBX20, TBX20_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q9UMR3
Notes: Ensembl ID: ENSG00000164532; Full protein sequence; TF family: T-box; Clone source: hORFeome
Length: 448
Pfam Domains:   102-289 T-box
Sequence: 
(in bold interface residues)		   1 MEFTASPKPQLSSRANAFSIAALMSSGGSKEKEATENTIKPLEQFVEKSSCAQPLGELTS   60
  61 LDAHGEFGGGSGSSPSSSSLCTEPLIPTTPIIPSEEMAKIACSLETKELWDKFHELGTEM  120
 121 IITKSGRRMFPTIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLP  180
 181 ARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHT  240
 241 ASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESV  300
 301 ESLIQKHSYARSPIRTYGGEEDVLGDESQTTPNRGSAFTTSDNLSLSSWVSSSSSFPGFQ  360
 361 HPQSLTALGTSTASIATPIPHPIQGSLPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPR  420
 421 YHHYFQQGPYAAIQGLRHSSAVMTPFV*
Interface Residues: 127, 265, 266, 276, 282, 285, 286
3D-footprint Homologues: 6f59_B, 1h6f_B, 4a04_B, 1xbr_B, 5flv_I, 2x6v_A, 3x1l_D
Binding Motifs: TBX20_full_1 wAGGTGTGAAr
TBX20_full_2 AGGTGTGAwgKTGTgA
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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