Transcription Factor

						

			
Accessions: 6jbq_F (3D-footprint 20231221)

			
Names: ECF RNA polymerase sigma-E factor, RPOE_ECOLI, Sigma-24
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0AGB6
Length: 186
Pfam Domains:     6-179 ECF sigma factor
    21-88 Sigma-70 region 2 
  125-176 Sigma-70, region 4
  131-176 Sigma-70, region 4
Sequence: 
(in bold interface residues)		   1 LTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSGDVPDVVQEAFIKAYRALDSF   60
  61 RGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIEAENFESGGALKEISNPENLMLS  120
 121 EELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIAAIMDCPVGTVRSRIFRAREAIDNK  180
 181 VQPLIR
Interface Residues: 52, 56, 60, 61, 63, 64, 67, 68, 69, 71, 72, 73, 76, 80, 152, 165, 167, 168, 171, 172
3D-footprint Homologues: 4lup_A, 6jhe_A, 2h27_A
Binding Motifs: 6jbq_F CGGAACTnnnnnnnnnnnnnAnTGTCnnAnC
Binding Sites: 6jbq_G
6jbq_H
			
Publications: Fang C, Li L, Shen L, Shi J, Wang S, Feng Y, Zhang Y. Structures and mechanism of transcription initiation by bacterial ECF factors. Nucleic Acids Res 47:7094-7104 (2019). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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