Transcription Factor

Accessions: T078286_1.02 (CISBP 1.02)
Names: Elf2, T078286_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Ets
Length: 533
Pfam Domains: 19-48 Transcription factor protein N terminal
148-230 Ets-domain
Sequence:
(in bold interface residues)
1 MATSLHEGPTNQLDLLIRAVEASVHSSNAHCTDKTIEAAEALLHMESPTCLRDSRSPVEV 60
61 FVPPCISTPEFIHAAMRPDVITETVVEVSTEESEPMDASPIPTSPDSHEPMKKKKVGRKP 120
121 KTQQSPVSNGSPELGIKKKAREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKL 180
181 VDSKAVSKLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKNIVVID 240
241 DDKSETCPEDLAAAADDKSLERVSLSAESLLKAATAVRGGKNSSPLNCSRAEKGVARVVN 300
301 ITSPTHDGSSRSPTTTAPVSAAAAPRTVRVAMQVPVVMTSLGQKISAVAVQSVNAGTGSP 360
361 LITSTSPASASSPKVVIQTVPTVMPASTENGDRITMQPAKIITIPATQLAQCQLQAKSNL 420
421 TGSGSINIVGTPLAVRALTPVSIAHGTPVMRLSVPAQQASGQTPPRVISALLKGPEGKSE 480
481 AKKQEHDVKTLQLVEEKGADGNKTVTHVVVVSAPSAIALPVTMKTEGLVTCEK
Interface Residues: 202, 203, 205, 206, 207, 209, 210, 224
3D-footprint Homologues: 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 1dux_F, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C, 4l18_B
Binding Motifs: M0708_1.02 ahsmGGAArt
Related annotations: PaperBLAST

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