Transcription Factor

Accessions: 1h8a_A (3D-footprint 20231221)
Names: C/EBP beta, CAAT/ENHANCER BINDING PROTEIN BETA, CCAAT/enhancer-binding protein beta, CEBPB_HUMAN, LAP, LIP, Liver activator protein, Liver-enriched inhibitory protein, Nuclear factor NF-IL6, TCF-5, Transcription factor 5
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P17676
Length: 68
Pfam Domains: 4-57 Basic region leucine zipper
5-63 bZIP transcription factor
Sequence:
(in bold interface residues)
1 VDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELST 60
61 LRNLFKQL
Interface Residues: 12, 15, 16, 18, 19, 22, 23
3D-footprint Homologues: 6mg1_B, 1nwq_C, 2c9l_Z, 2dgc_A
Binding Motifs: 1h8a_ABC TCCGTTAnnnGTTGCGCCAC
Publications: Tahirov T.H, Sato K, Ichikawa-Iwata E, Sasaki M, Inoue-Bungo T, Shiina M, Kimura K, Takata S, Fujikawa A, Morii H, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Mechanism of c-Myb-C/EBP beta cooperation from separated sites on a promoter. Cell 108:57-70 (2002). [Pubmed]
Related annotations: PaperBLAST

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