Transcription Factor

						

			
Accessions: T081998_1.02 (CISBP 1.02), FOXC1_MOUSE (HOCOMOCO 10)

			
Names: Foxc1, T081998_1.02;, Forkhead box protein C1, Forkhead-related protein FKHL7, Forkhead-related transcription factor 3, FOXC1_MOUSE, FREAC-3, Mesoderm/mesenchyme forkhead 1, MF-1, Transcription factor FKH-1
Organisms: Mus musculus
Libraries: CISBP 1.02 1, HOCOMOCO 10 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Notes: experiment type:PBM, family:Forkhead
Length: 553
Pfam Domains:    78-173 Fork head domain
Sequence: 
(in bold interface residues)		   1 MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGSM   60
  61 ARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQ  120
 121 GWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAV  180
 181 KDKEEKGRLHLQEPPPPQAGRQPAPAPPEQAEGSAPGPQPPPVRIQDIKTENGTCPSPPQ  240
 241 PLSPAAALGSGSAATVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDAAEPAPPPQPAP  300
 301 PPHHSQGFSVDNIMTSLRGSPQGSAAELGSGLLASAAASSRAGIAPPLALGAYSPGQSSL  360
 361 YSSPCSQSSSAGSSGGGGGGGGGGGGSSSAAGTGGAATYHCNLQAMSLYAAGERGGHLQG  420
 421 PAGGAGSAAVDDPLPDYSLPPATSSSSSSLSHGGGGQEASHHPASHQGRLTSWYLNQAGG  480
 481 DLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPASQSLY  540
 541 RTSGAFVYDCSKF
Interface Residues: 101, 118, 120, 121, 123, 124, 125, 127, 128, 129, 131, 132, 141, 148, 169, 173
3D-footprint Homologues: 8vfz_O, 3l2c_A, 8bzm_E, 7vox_H, 2hdc_A, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 8sro_B, 3qrf_G
Binding Motifs: M0734_1.02 wrwrtmAAyA
FOXC1_MOUSE.H10MO.C|M01097 crwTGTTTAYtTwrs
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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