Transcription Factor

Accessions: T049094_1.02 (CISBP 1.02)
Names: T049094_1.02;, Zscan10
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 702
Pfam Domains: 38-86 SCAN domain
301-323 Zinc finger, C2H2 type
301-323 C2H2-type zinc finger
316-339 Zinc-finger double domain
329-351 C2H2-type zinc finger
329-351 Zinc finger, C2H2 type
357-379 C2H2-type zinc finger
357-379 Zinc finger, C2H2 type
357-376 C2H2-type zinc finger
403-423 C2H2-type zinc finger
403-423 Zinc finger, C2H2 type
403-423 C2H2-type zinc finger
415-457 Zinc-finger double domain
447-470 C2H2-type zinc finger
447-470 Zinc finger, C2H2 type
447-462 C2H2-type zinc finger
462-486 Zinc-finger double domain
476-498 C2H2-type zinc finger
476-498 Zinc finger, C2H2 type
493-514 Zinc-finger double domain
504-526 C2H2-type zinc finger
504-526 Zinc finger, C2H2 type
504-513 C2H2-type zinc finger
519-542 Zinc-finger double domain
532-554 C2H2-type zinc finger
532-554 C2H2-type zinc finger
546-570 Zinc-finger double domain
561-582 Zinc finger, C2H2 type
561-582 C2H2-type zinc finger
574-599 Zinc-finger double domain
588-610 Zinc finger, C2H2 type
588-610 C2H2-type zinc finger
588-610 C2H2-type zinc finger
602-626 Zinc-finger double domain
616-638 Zinc finger, C2H2 type
616-638 C2H2-type zinc finger
616-626 C2H2-type zinc finger
630-659 Zinc-finger double domain
650-671 Zinc finger, C2H2 type
650-671 C2H2-type zinc finger
650-667 C2H2-type zinc finger
663-688 Zinc-finger double domain
677-699 Zinc finger, C2H2 type
677-699 C2H2-type zinc finger
677-699 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MLAEPVPDALEQEHPGAVKLEEDEVGEEDPRLAESRPRPEVAHQLFRCFQYQEDMGPRAS 60
61 LGRLRELCNHWLRPALHTKKQILELLDFSFSAGKNAPADIISEEQNSPSQVPSHSPQTEL 120
121 PSEEIPALHPLNELPPPQPAPIRPAEPEEWRLAPSSNWPMSPEPQEILQDPRESNPSQGP 180
181 SWLEENSRDQELAAVLESLTFEDTSEKRAWPANPLGFGSRMPDNEELKVEEPKVTTWPVV 240
241 IGAESQTEKPEVAGEPLTQTVGQETSSTGWGGTPADGSEVVKAHQLQSHPNLQPHPSSRS 300
301 FRCLWCGKTFGRSSILKLHMRTHTDERPHACHLCNRRFRQSSHLTKHLLTHSSEPAFRCA 360
361 ECNQGFQRRSSLMQHLLAHAQGKNLTPNPEGKTKVPEMAAVLCSHCGQTFKRRSSLKRHL 420
421 RNHAKDKDHLSSEDPGSLSSSQESNPYVCSDCGKAFRQSEQLMIHTRRVHTRERPFSCQV 480
481 CGRCFTQNSQLISHQQIHTGEKPHACPQCSKRFVRRAGLARHLLTHGSLRPYHCAQCGKS 540
541 FRQMRDLTRHVRCHTGEKPCRCNECGEGFTQNAHLARHQRIHTGEKPHACDICGHRFRNS 600
601 SNLARHRRSHTGERPYSCPTCGRSFRRNAHLQRHLITHTGSKQEKEVPQECPECGKSFNR 660
661 SCNLLRHLLVHTGARPYSCALCGRSFSRNSHLLRHLRTHARE
Interface Residues: 311, 312, 314, 315, 318, 339, 340, 341, 342, 343, 345, 346, 350, 368, 369, 370, 371, 374, 382, 412, 414, 415, 418, 458, 460, 461, 464, 468, 487, 489, 490, 492, 493, 515, 516, 517, 518, 521, 524, 542, 543, 544, 545, 546, 548, 549, 555, 569, 570, 571, 572, 573, 574, 576, 577, 579, 580, 581, 583, 598, 599, 600, 601, 602, 604, 605, 606, 607, 626, 627, 628, 629, 630, 631, 632, 633, 634, 642, 645, 646, 659, 660, 661, 662, 663, 665, 666, 688, 690, 691, 694
3D-footprint Homologues: 3uk3_C, 7w1m_H, 5k5i_A, 6u9q_A, 7y3m_I, 8ssu_A, 8ssq_A, 2gli_A, 5v3j_F, 2lt7_A, 6a57_A, 2kmk_A, 7ysf_A, 5yel_A, 1tf3_A, 1tf6_A, 4x9j_A, 1g2f_F, 5ei9_F, 6e94_A, 1ubd_C, 7n5w_A, 6jnm_A, 5kkq_D, 5yj3_D, 7txc_E, 1llm_D, 6blw_A, 8h9h_G, 2jpa_A, 7y3l_A, 8cuc_F, 5kl3_A, 2wbs_A, 6ml4_A, 4m9v_C, 2drp_D, 1yuj_A, 1f2i_J, 8gn3_A
Binding Motifs: M0398_1.02 aGgrAGTGCaa
Related annotations: PaperBLAST

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