Transcription Factor
| Accessions: | SOX12 (HT-SELEX2 May2017) |
| Names: | ENSG00000177732, SOX12 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: HMG experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: HMG experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2 |
| Length: | 107 |
| Pfam Domains: | 17-85 HMG (high mobility group) box 18-75 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 EEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQD 60 61 SEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGGS |
| Interface Residues: | 19, 22, 24, 25, 28, 32, 43, 44, 45, 48, 86, 90, 100 |
| 3D-footprint Homologues: | 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 1hry_A, 3tq6_B, 1ckt_A |
| Binding Motifs: | SOX12_2 aCCGAACAATg SOX12_methyl_1 AccGAACAATr |
| Related annotations: | PaperBLAST |
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