Transcription Factor
| Accessions: | ZN350_HUMAN (HOCOMOCO 10), Q9GZX5 (JASPAR 2024) |
| Names: | KRAB zinc finger protein ZFQR, Zinc finger and BRCA1-interacting protein with a KRAB domain 1, Zinc finger protein 350, Zinc finger protein ZBRK1, ZN350_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9GZX5 |
| Length: | 532 |
| Pfam Domains: | 8-48 KRAB box 206-215 C2H2-type zinc finger 206-228 Zinc finger, C2H2 type 221-245 Zinc-finger double domain 234-256 C2H2-type zinc finger 234-256 Zinc finger, C2H2 type 249-272 Zinc-finger double domain 261-271 C2H2-type zinc finger 262-284 C2H2-type zinc finger 262-284 Zinc finger, C2H2 type 277-299 Zinc-finger double domain 290-299 C2H2-type zinc finger 290-312 C2H2-type zinc finger 290-312 Zinc finger, C2H2 type 304-327 Zinc-finger double domain 318-340 C2H2-type zinc finger 318-340 Zinc finger, C2H2 type 335-356 Zinc-finger double domain 346-368 C2H2-type zinc finger 346-368 Zinc finger, C2H2 type 361-385 Zinc-finger double domain 373-396 C2H2-type zinc finger 374-396 C2H2-type zinc finger 374-396 Zinc finger, C2H2 type 391-413 Zinc-finger double domain 402-424 Zinc finger, C2H2 type 402-422 C2H2-type zinc finger 404-424 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MIQAQESITLEDVAVDFTWEEWQLLGAAQKDLYRDVMLENYSNLVAVGYQASKPDALFKL 60 61 EQGEQLWTIEDGIHSGACSDIWKVDHVLERLQSESLVNRRKPCHEHDAFENIVHCSKSQF 120 121 LLGQNHDIFDLRGKSLKSNLTLVNQSKGYEIKNSVEFTGNGDSFLHANHERLHTAIKFPA 180 181 SQKLISTKSQFISPKHQKTRKLEKHHVCSECGKAFIKKSWLTDHQVMHTGEKPHRCSLCE 240 241 KAFSRKFMLTEHQRTHTGEKPYECPECGKAFLKKSRLNIHQKTHTGEKPYICSECGKGFI 300 301 QKGNLIVHQRIHTGEKPYICNECGKGFIQKTCLIAHQRFHTGKTPFVCSECGKSCSQKSG 360 361 LIKHQRIHTGEKPFECSECGKAFSTKQKLIVHQRTHTGERPYGCNECGKAFAYMSCLVKH 420 421 KRIHTREKQEAAKVENPPAERHSSLHTSDVMQEKNSANGATTQVPSVAPQTSLNISGLLA 480 481 NRNVVLVGQPVVRCAASGDNRGFAQDRNLVNAVNVVVPSVINYVLFYVTENP |
| Interface Residues: | 141, 143, 148, 195, 216, 217, 219, 220, 222, 223, 225, 226, 229, 244, 245, 246, 247, 248, 251, 252, 262, 272, 273, 274, 275, 276, 277, 278, 279, 280, 300, 301, 302, 303, 304, 306, 307, 328, 329, 330, 331, 332, 335, 338, 356, 357, 358, 359, 360, 361, 363, 369, 383, 384, 385, 386, 387, 388, 390, 391, 395, 412, 413, 414, 415, 416, 419 |
| 3D-footprint Homologues: | 6j9c_D, 7w1m_H, 6jnm_A, 2gli_A, 8ssq_A, 5kkq_D, 6u9q_A, 8ssu_A, 5v3j_F, 2lt7_A, 6a57_A, 2jpa_A, 7n5w_A, 2wbs_A, 5kl3_A, 5k5i_A, 2drp_D, 4m9v_C, 8h9h_G, 7ysf_A, 5yel_A, 1ubd_C, 2kmk_A, 1tf3_A, 8cuc_F, 7y3l_A, 3uk3_C, 1tf6_A, 6blw_A, 5k5l_F, 7y3m_I, 5ei9_F, 7txc_E, 6ml4_A, 6e94_A, 4x9j_A, 1f2i_J, 1g2f_F, 8gn3_A, 1llm_D, 5yj3_D |
| Binding Motifs: | ZN350_HUMAN.H10MO.C|M01628 asGGGvvgcArdkvkyTkkkksCs UN0612.1 taGGTcATAAAAggrm UN0612.2 GGTcATAAAAgg |
| Binding Sites: | UN0612.1.1 UN0612.1.10 / UN0612.1.12 UN0612.1.11 UN0612.1.12 / UN0612.1.13 UN0612.1.13 / UN0612.1.14 UN0612.1.14 / UN0612.1.19 UN0612.1.15 / UN0612.1.20 UN0612.1.16 UN0612.1.17 UN0612.1.18 UN0612.1.19 UN0612.1.2 UN0612.1.20 UN0612.1.3 UN0612.1.4 / UN0612.1.5 UN0612.1.5 / UN0612.1.6 UN0612.1.6 / UN0612.1.8 UN0612.1.7 / UN0612.1.9 UN0612.1.10 / UN0612.1.8 UN0612.1.11 / UN0612.1.9 UN0612.1.15 UN0612.1.16 UN0612.1.17 UN0612.1.18 UN0612.1.4 UN0612.1.7 UN0612.2.1 UN0612.2.10 UN0612.2.11 UN0612.2.12 UN0612.2.13 UN0612.2.14 / UN0612.2.4 / UN0612.2.5 UN0612.2.15 UN0612.2.16 / UN0612.2.7 UN0612.2.17 UN0612.2.18 UN0612.2.19 UN0612.2.2 UN0612.2.20 UN0612.2.3 UN0612.2.6 UN0612.2.8 UN0612.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.