Transcription Factor

Accessions: 5d8l_D (3D-footprint 20231221)
Names: Heat shock factor protein 2, Heat shock transcription factor 2, HSF 2, HSF2_HUMAN, HSTF 2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q03933
Length: 97
Pfam Domains: 4-96 HSF-type DNA-binding
(in bold interface residues)
Interface Residues: 6, 8, 9, 11, 46, 47, 49, 50, 55, 57, 58, 59, 61, 62, 95
3D-footprint Homologues: 5x2h_A, 5hdn_C, 3hts_B, 5d5v_B, 5d5w_B, 7dci_A
Binding Motifs: 5d8l_DF AGAaAsnntTCT
Publications: Jaeger AM, Pemble CW 4th, Sistonen L, Thiele DJ. Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors. Nat Struct Mol Biol 23:147-54 (2016). [Pubmed]
Related annotations: PaperBLAST

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