Transcription Factor

Accessions: 1hbx_E (3D-footprint 20231221)
Names: SERUM RESPONSE FACTOR, SRF_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P11831
Length: 89
Pfam Domains: 15-65 SRF-type transcription factor (DNA-binding and dimerisation domain)
Sequence:
(in bold interface residues)
1 KPGKKTRGRVKIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLTGTQVLLLVASETGHV 60
61 YTFATRKLQPMITSETGKALIQTCLNSPD
Interface Residues: 6, 9, 10, 21, 24, 25, 29
3D-footprint Homologues: 1hbx_A, 1c7u_A, 7x1n_C, 1n6j_A, 1mnm_A
Binding Motifs: 1hbx_DEH CTAATTAGsanTTCCG
Publications: Hassler M., Richmond T. J. The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex.. EMBO J. 20:3018-3028 (2001). [Pubmed]
Related annotations: PaperBLAST

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