Transcription Factor
| Accessions: | Q9QZ59 (JASPAR 2024) |
| Names: | DMRT1_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 374 |
| Pfam Domains: | 70-116 DM DNA binding domain 128-200 Double-sex mab3 related transcription factor 1 |
| Sequence: (in bold interface residues) | 1 MPNDDTFGKPSTPTEVPHAPGAPPQGKAGGYSKAAGAMAGAAGGSGAGGSGGASGSGPSG 60 61 LGSGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCSLIAERQRVMAAQVALR 120 121 RQQAQEEELGISHPIPLPSAAELLVKRENNASNPCLMAENSSSAQPPPASTPTPAASEGR 180 181 MVIQDIPAVTSRGHMENTSDLVSDPAYYSSFYQPSLFPYYNNLYNYPQYSMALSAESSSG 240 241 EVGNSLGGSPVKNSLRSLPAPYVPAQTGNQWQMKTSESRHPVSSQYRMHSYYGPPSYLGQ 300 301 SMSQIFTFEEGPSYSEAKASVFSPPSSQDSGLVSLSSSSPMSNESSKGVLECESASSEPS 360 361 SYAVNQVLEEDEDE |
| Interface Residues: | 70, 109, 113, 116, 117, 120, 121 |
| 3D-footprint Homologues: | 4yj0_C |
| Binding Motifs: | MA1603.1 gwtACAAWGTawc MA1603.2 tACAAWGTa |
| Binding Sites: | MA1603.1.1 / MA1603.1.2 / MA1603.1.3 MA1603.1.10 MA1603.1.11 MA1603.1.12 / MA1603.1.6 MA1603.1.13 / MA1603.1.7 MA1603.1.14 MA1603.1.15 / MA1603.1.5 MA1603.1.16 MA1603.1.17 / MA1603.1.18 / MA1603.1.6 MA1603.1.18 MA1603.1.19 / MA1603.1.7 MA1603.1.20 / MA1603.1.8 MA1603.1.3 / MA1603.1.8 MA1603.1.4 / MA1603.1.9 MA1603.1.4 / MA1603.1.5 MA1603.1.13 MA1603.1.10 MA1603.1.11 MA1603.1.12 MA1603.1.14 MA1603.1.15 MA1603.1.16 MA1603.1.19 MA1603.1.2 MA1603.1.20 MA1603.1.9 MA1603.2.1 / MA1603.2.14 / MA1603.2.3 MA1603.2.10 / MA1603.2.13 / MA1603.2.9 MA1603.2.11 / MA1603.2.12 MA1603.2.15 / MA1603.2.16 / MA1603.2.17 MA1603.2.18 / MA1603.2.19 / MA1603.2.6 / MA1603.2.7 / MA1603.2.8 MA1603.2.2 MA1603.2.20 MA1603.2.4 MA1603.2.5 |
| Publications: | Murphy MW, Lee JK, Rojo S, Gearhart MD, Kurahashi K, Banerjee S, Loeuille GA, Bashamboo A, McElreavey K, Zarkower D, Aihara H, Bardwell VJ. An ancient protein-DNA interaction underlying metazoan sex determination. Nat Struct Mol Biol 22:442-51 (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.