Transcription Factor

Accessions: Jdp2_DBD (HumanTF 1.0), UP00103A (UniPROBE 20160601)
Names: Jdp2, JDP2_MOUSE, Jun dimerization protein 2, Jundm2, Jundp2, TIF
Organisms: Mus musculus
Libraries: HumanTF 1.0 1, UniPROBE 20160601 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P97875
Description: Jun dimerization protein 2: Mus musculus Jun dimerization protein 2 (Jundp2-pending), mRNA
Notes: Ensembl ID: ENSMUSG00000034271; DNA-binding domain sequence; TF family: bZIP; Clone source: Hughes lab.
Length: 95
Pfam Domains: 16-74 bZIP transcription factor
17-70 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 VKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAEL 60
61 KTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTP
Interface Residues: 24, 25, 28, 29, 31, 32, 35, 36, 39
3D-footprint Homologues: 7x5e_F, 1skn_P, 2wt7_A, 4eot_A, 7x5e_E, 1nwq_C, 5t01_B, 5vpe_C, 5vpe_D
Binding Motifs: UP00103A_1 csgaTGACGTCAycry
Jdp2_DBD_1 ATGASTCAT
Jdp2_DBD_2 gATGACGTCAyc
UP00103A_2 mdkgrTGAsTCAymam
Binding Sites: GTGACTCA
TGACGTAA
TGACATCA
AATGACGT
ACGTAATC
ACGTCACC
ACGTCATA
ACGTCATC
ACGTCATG
ATGACGAA
ATGACGCA
ATGACGTA
ATGACGTC
ATGACGTG
ATGACTAA
ATGACTCA
ATGAGTCA
CGTCATCA
GTGACGTA
GTGAGTCA
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.