Transcription Factor
| Accessions: | Q2VY69 (JASPAR 2024) |
| Names: | ZN284_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q2VY69 |
| Length: | 593 |
| Pfam Domains: | 8-48 KRAB box 193-213 Zinc-finger double domain 203-225 Zinc finger, C2H2 type 203-225 C2H2-type zinc finger 203-221 C2H2-type zinc finger 218-242 Zinc-finger double domain 231-253 Zinc finger, C2H2 type 231-253 C2H2-type zinc finger 231-243 C2H2-type zinc finger 247-269 Zinc-finger double domain 258-279 C2H2-type zinc finger 259-281 C2H2-type zinc finger 259-281 Zinc finger, C2H2 type 274-297 Zinc-finger double domain 287-309 C2H2-type zinc finger 287-307 C2H2-type zinc finger 287-309 Zinc finger, C2H2 type 301-325 Zinc-finger double domain 315-333 C2H2-type zinc finger 329-354 Zinc-finger double domain 342-361 C2H2-type zinc finger 343-365 C2H2-type zinc finger 360-380 Zinc-finger double domain 371-394 C2H2-type zinc finger 371-393 Zinc finger, C2H2 type 386-409 Zinc-finger double domain 427-449 C2H2-type zinc finger 427-449 Zinc finger, C2H2 type 441-464 Zinc-finger double domain 455-474 C2H2-type zinc finger 455-477 Zinc finger, C2H2 type 472-493 Zinc-finger double domain 483-505 Zinc finger, C2H2 type 483-493 C2H2-type zinc finger 483-505 C2H2-type zinc finger 498-520 Zinc-finger double domain 529-548 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MTMFKEAVTFKDVAVVFTEEELGLLDVSQRKLYRDVMLENFRNLLSVGHQLSHRDTFHFQ 60 61 REEKFWIMETATQREGNSGGKIQTELESVPETGPHEEWSCQQIWEQTASELTRPQDSISS 120 121 SQFSTQGDVPSQVDAGLSIIHIGETPSEHGKCKKFFSDVSILDLHQQLHSGKISHTCNEY 180 181 RKRFCYSSALCLHQKVHMGEKRYKCDVCSKAFSQNSQLQTHQRIHTGEKPFKCEQCGKSF 240 241 SRRSGMYVHCKLHTGEKPHICEECGKAFIHNSQLREHQRIHTGEKPFKCYICGKSFHSRS 300 301 NLNRHSMVHMQEKSFRCDTCSNSFGQRSALNSHCMDHTKEKLYKCEECGRSFTCRQDLCK 360 361 HQMDHTGDKPYNCNVCGKGFRWSSCLSRHQRVHNGETTFKCDGCGKRFYMNSQGHSHQRA 420 421 YREEELYKCQKCGKGYISKFNLDLHQRVHTGERPYNCKECGKSFRWASGILRHKRLHTGE 480 481 KPFKCEECGKRFTENSKLRFHQRIHTGEKPYKCEECGKGFRWASTHLTHQRLHSREKLFQ 540 541 CEDCGKSSEHSSCLQDQQSDHSGEKTSKCEDCGKRYERRLNLDMILSLFLNDI |
| Interface Residues: | 186, 188, 189, 203, 213, 214, 215, 216, 217, 220, 224, 241, 242, 243, 244, 245, 246, 247, 248, 269, 270, 271, 272, 273, 276, 280, 298, 299, 300, 301, 303, 304, 308, 325, 326, 327, 328, 329, 331, 332, 354, 356, 357, 360, 381, 382, 383, 384, 385, 388, 391, 410, 412, 413, 416, 420, 422, 436, 437, 438, 439, 440, 441, 443, 444, 446, 447, 448, 450, 465, 466, 467, 468, 469, 471, 472, 473, 493, 494, 495, 496, 497, 498, 499, 500, 501, 521, 522, 523, 524, 525, 528 |
| 3D-footprint Homologues: | 2i13_A, 2kmk_A, 3uk3_C, 7n5w_A, 7w1m_H, 2drp_D, 1f2i_J, 8ssu_A, 1g2f_F, 5kkq_D, 5yel_A, 4x9j_A, 1llm_D, 5kl3_A, 8ssq_A, 7eyi_G, 8h9h_G, 7y3m_I, 7ysf_A, 5und_A, 6ml4_A, 2gli_A, 7txc_E, 1ubd_C, 8cuc_F, 1tf3_A, 7y3l_A, 5k5i_A, 8gn3_A, 5v3j_F, 1tf6_A, 6wmi_A, 6jnm_A, 6blw_A, 5ei9_F, 6e94_A, 6a57_A, 2jpa_A, 1mey_C, 6u9q_A, 2wbs_A, 4m9v_C, 2lt7_A, 5yj3_D |
| Binding Motifs: | UN0174.1 gcTGAGGCAGrA |
| Binding Sites: | UN0174.1.1 UN0174.1.10 / UN0174.1.6 UN0174.1.11 UN0174.1.12 / UN0174.1.8 UN0174.1.13 / UN0174.1.9 UN0174.1.10 / UN0174.1.14 UN0174.1.15 UN0174.1.11 / UN0174.1.16 UN0174.1.12 / UN0174.1.17 UN0174.1.13 / UN0174.1.18 UN0174.1.19 UN0174.1.2 UN0174.1.14 / UN0174.1.20 UN0174.1.1 / UN0174.1.3 UN0174.1.2 / UN0174.1.4 UN0174.1.3 / UN0174.1.5 UN0174.1.6 UN0174.1.7 UN0174.1.8 UN0174.1.5 / UN0174.1.9 UN0174.1.15 UN0174.1.16 UN0174.1.17 UN0174.1.18 UN0174.1.19 UN0174.1.20 UN0174.1.4 UN0174.1.7 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.