Transcription Factor
| Accessions: | UP00453A (UniPROBE 20160601), P24813 (JASPAR 2024) |
| Names: | Cad1, CADmium resistance, AP-1-like transcription factor YAP2, AP2_YEAST, Cadmium resistance protein 1, Transcription factor CAD1 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Description: | CADmium resistance : AP-1-like basic leucine zipper (bZIP) transcriptional activator involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA |
| Length: | 409 |
| Pfam Domains: | 46-83 bZIP transcription factor 100-406 Transcription factor PAP1 |
| Sequence: (in bold interface residues) | 1 MGNILRKGQQIYLAGDMKKQMLLNKDGTPKRKVGRPGRKRIDSEAKSRRTAQNRAAQRAF 60 61 RDRKEAKMKSLQERVELLEQKDAQNKTTTDFLLCSLKSLLSEITKYRAKNSDDERILAFL 120 121 DDLQEQQKRENEKGTSTAVSKAAKELPSPNSDENMTVNTSIEVQPHTQENEKVMWNIGSW 180 181 NAPSLTNSWDSPPGNRTGAVTIGDESINGSEMPDFSLDLVSNDRQTGLEALDYDIHNYFP 240 241 QHSERLTAEKIDTSACQCEIDQKYLPYETEDDTLFPSVLPLAVGSQCNNICNRKCIGTKP 300 301 CSNKEIKCDLITSHLLNQKSLASVLPVAASHTKTIRTQSEAIEHISSAISNGKASCYHIL 360 361 EEISSLPKYSSLDIDDLCSELIIKAKCTDDCKIVVKARDLQSALVRQLL |
| Interface Residues: | 6, 34, 35, 38, 49, 52, 53, 54, 56, 57, 60, 61 |
| 3D-footprint Homologues: | 3q05_B, 1gd2_G, 1dh3_C |
| Binding Motifs: | MA0279.1 ATTArTAAkC UP00453A_1 / UP00453A_2 ttswwwgATTAsTAATmdwavwr UP00453A_3 ATTACGTAA MA0279.2 wttGmTTACTAATmmd MA0279.3 tGmTTACTAAT |
| Binding Sites: | CTGACTAA AATTAATA ATTAATAA ATTAATCA ATTACTAA ATTAGTAA ATTAGTCA CTTACTAA CTTAGTAA GTTAGTAA TAATATTA TTACATAA TTACGTAA TTATATAA AAGCGCTT ATTACAAA ATTTGTCA CTGACAAA CTTATTAA GCTTACTA MA0279.2.1 MA0279.2.10 / MA0279.2.18 MA0279.2.11 / MA0279.2.19 MA0279.2.12 / MA0279.2.20 MA0279.2.13 MA0279.2.14 MA0279.2.15 MA0279.2.16 MA0279.2.17 MA0279.2.18 MA0279.2.19 MA0279.2.2 MA0279.2.20 MA0279.2.2 / MA0279.2.3 MA0279.2.4 MA0279.2.5 / MA0279.2.6 MA0279.2.6 / MA0279.2.8 MA0279.2.12 / MA0279.2.7 MA0279.2.14 / MA0279.2.8 MA0279.2.16 / MA0279.2.9 MA0279.2.10 MA0279.2.11 MA0279.2.13 MA0279.2.15 MA0279.2.17 MA0279.2.3 MA0279.2.5 MA0279.2.7 MA0279.2.9 MA0279.3.1 MA0279.3.10 MA0279.3.11 MA0279.3.12 MA0279.3.13 MA0279.3.14 MA0279.3.15 / MA0279.3.8 / MA0279.3.9 MA0279.3.16 MA0279.3.17 MA0279.3.18 MA0279.3.19 MA0279.3.2 MA0279.3.20 MA0279.3.3 MA0279.3.4 MA0279.3.5 MA0279.3.6 MA0279.3.7 |
| Publications: | Gordân R, Murphy KF, McCord RP, Zhu C, Vedenko A, Bulyk ML. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol : (2011). [Pubmed] Pachkov M, Erb I, Molina N, van Nimwegen E. SwissRegulon: a database of genome-wide annotations of regulatory sites. Nucleic acids research 35:D127-31 (2007). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.