Transcription Factor
| Accessions: | UP00057A (UniPROBE 20160601) |
| Names: | GENA 29, HPE5, Ku, odd-paired homolog, Zic finger protein of the cerebellum 2, Zic2, Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q62520 |
| Description: | Zic finger protein of the cerebellum 2: Mus musculus Zic finger protein of the cerebellum 2 (Zic2) |
| Length: | 180 |
| Pfam Domains: | 22-41 Zinc finger, C2H2 type 23-41 C2H2-type zinc finger 52-77 Zinc finger, C2H2 type 56-77 C2H2-type zinc finger 70-95 Zinc-finger double domain 83-107 C2H2-type zinc finger 83-107 Zinc finger, C2H2 type 99-126 Zinc-finger double domain 113-137 Zinc finger, C2H2 type 113-137 C2H2-type zinc finger 131-154 Zinc-finger double domain 143-165 Zinc finger, C2H2 type 143-165 C2H2-type zinc finger 144-163 Zinc-finger of C2H2 type |
| Sequence: (in bold interface residues) | 1 CIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPRE 60 61 GKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGC 120 121 DRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASS 180 |
| Interface Residues: | 28, 29, 31, 32, 35, 65, 66, 67, 68, 69, 71, 72, 76, 95, 96, 97, 98, 99, 101, 102, 103, 104, 105, 107, 108, 111, 125, 126, 127, 128, 129, 130, 131, 132, 133, 136, 153, 154, 155, 156, 157, 158, 159, 160, 161 |
| 3D-footprint Homologues: | 5v3j_F, 1ubd_C, 7n5w_A, 1tf3_A, 7w1m_H, 8cuc_F, 8ssu_A, 1tf6_A, 6ml4_A, 8gn3_A, 5kkq_D, 4x9j_A, 5ei9_F, 8ssq_A, 2gli_A, 7eyi_G, 5k5i_A, 2i13_A, 6e94_A, 7ysf_A, 6wmi_A, 5und_A, 2lt7_A, 7y3l_A, 6jnm_A, 3uk3_C, 1llm_D, 6blw_A, 2v6e_B, 6u9q_A, 5yel_A, 1mey_C, 5kl3_A, 2drp_D, 1f2i_J, 2kmk_A, 1g2f_F, 8h9h_G, 7y3m_I, 6a57_A, 2jpa_A, 7txc_E, 2wbs_A, 5yj3_D, 4m9v_C |
| Binding Motifs: | UP00057A_1 bmCCCCCgGGGGggt UP00057A_2 ycdCvCAGCAkGara |
| Binding Sites: | ACCCCCCA ACCCCCCG ACCCCCTG ACGGGGGG AGACCCCC CAGCGGGG CCACGGGG CCAGGGGG CCCCCCCG CCCCCCGC CCCCCCGG CCCCCGGG CCCCGCGG CCCCGGGG CGGGGGGC GACCCCCC GCCCCCCC GGACCCCC GGCCCCCC GGGGGGTA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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