Transcription Factor
| Accessions: | MEIS2_MOUSE (HOCOMOCO 10), P97367 (JASPAR 2024) |
| Names: | Homeobox protein Meis2, Meis1-related protein 1, MEIS2_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 477 |
| Pfam Domains: | 278-333 Homeobox domain 294-333 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 60 61 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 120 121 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 180 181 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 240 241 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 300 301 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS 360 361 PEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMGMAQPSYTPPQMTPHPTQLR 420 421 HGPPMHSYLPSHPHHPAMVMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ |
| Interface Residues: | 276, 277, 279, 280, 324, 325, 328, 329, 330, 332, 333, 364, 367 |
| 3D-footprint Homologues: | 4j19_B, 6fqp_B, 1puf_B, 1au7_A, 1le8_A, 7q3o_C, 4xrs_G, 3rkq_B, 5hod_A, 2d5v_B, 6fqq_E, 1le8_B, 5zfz_A, 3cmy_A, 1fjl_B, 4xrm_B, 1mnm_C, 6a8r_A, 3lnq_A, 1k61_B, 8g87_X |
| Binding Motifs: | MEIS2_MOUSE.H10MO.B|M01209 tTGACAGsTkTcm PH0104.1 warsAsCTGTCAAway |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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